摘要
目的:了解乌鲁木齐市维吾尔族儿童先天性心脏病的相关危险因素,为制定预防和干预措施提供依据。方法:选取入院确诊的维吾尔族先天性心脏病患儿258例为病例组,同时收集无心脏缺陷的患儿173例为对照组,应用调查问卷收集患者及父母的相关信息。利用SPSS 17.0软件对两组的资料进行统计分析。结果:维吾尔族先天性心脏病类型的前3位依次为房间隔缺损、室间隔缺损和动脉导管未闭;病例组患者的母亲孕龄平均为(30.93±6.41)岁,孕次(2.02±1.11)次,产次(1.62±1.00)次,均高于对照组,差异均有统计学意义(P<0.05);病例组患者的母亲小学和文盲比例、服用避孕药比例、流产比例、情绪处于紧张和抑郁的比例均高于对照组,服用营养补充剂的比例低于对照组,差异均有统计学意义(P<0.05);病例组患者的父亲小学和文盲比例及吸烟比例高于对照组,差异均有统计学意义(P<0.05)。结论:母亲服用避孕药,孕次增加、孕期情绪紧张或抑郁、父亲文化程度低和吸烟是维吾尔族先天性心脏病的危险因素,应加强孕前及孕期夫妻双方的综合干预。
Objective： To understand the related risk factors of congenital heart disease（ CHD） in Uygur children in Urumqi,provide a basis for making preventive and intervention measures. Methods： A total of 258 Uygur children with CHD were selected as case group,173 Uygur children without heart defects were selected as control group,the information about the children and their parents were collected by a questionnaire. SPSS 17. 0 software was used to analyzed the data in the two groups statistically. Results： The top three types of CHD among Uygur children were atrial septal defect（ ASD）,ventricular septal defect（ VSD） and patent ductus arteriosus. The mean gestational age,gravidity and parity in case group were（ 30. 93 ± 6. 41） years old,（ 2. 02 ± 1. 11） times and（ 1. 62 ± 1. 00） times,respectively,which were statistically significantly higher than those in control group（ P〈0. 05）; the proportions of low educational level（ primary school and illiterate）,taking oral contraceptive pills,abortion,emotional stress and depression of mothers in case group were higher than those in control group,while the proportion of taking nutritious supplementary in case group was lower than that in control group,there were statistically significant differences（ P〈0. 05）; the proportions of low educational level（ primary school and illiterate） and smoking of fathers in case group were statistically significantly higher than those in control group（ P〈0. 05）. Conclusion： Taking oral contraceptive pills,high gravidity,emotional stress and depression during pregnancy of mothers and low educational level and smoking of fathers are risk factors of CHD in Uygur children in Urumqi; comprehensive intervention should be strengthened before and during pregnancy among the couples.
出处
《中国妇幼保健》
CAS
2015年第3期438-440,共3页
Maternal and Child Health Care of China
基金
国家自然科学基金〔30901474〕
