摘要
高同型半胱氨酸血症(HHcy)是由同型半胱氨酸(Hcy)代谢异常引起的。HHcy既是心脑血管疾病的独立危险因素,也与多种神经退行性疾病和精神疾病密切相关。HHcy主要通过血管和神经毒性发挥致病作用。本文就近年来HHcy的致神经毒性作用的机制做一综述。
Hyperhomocysteinemia( HHcy) is caused by abnormal metabolism of homocysteine( Hcy). HHcy is not only an independent risk factor for cardiovascular and cerebrovascular diseases,but also closely correlated with a variety of neurodegenerative and mental diseases. HHcy mainly plays a pathogenic role by vascular and neuron neurotoxicity. In this article,we review the mechanisms of HHcy neurotoxicity in recent years.
出处
《检验医学》
CAS
2014年第12期1263-1267,共5页
Laboratory Medicine
基金
上海市虹口区卫生和计划生育委员会科研课题(虹卫1304-47)
