摘要
目的:调查分析国内慢性荨麻疹临床疗效判断标准。方法:采用频数分析、K-均值聚类分析等方法,分析目前国内慢性荨麻疹相关疗效判断标准的使用情况与适用范围。结果:符合纳入标准的文献857篇,文献中症状评估指标和疗效评价标准各不相同,采用症状体征下降指数(SSRI)四级分级法的文献549篇(占64.17%)。采用K-均值聚类统计分析后发现,以治愈(100%≥SSRI>90%)、好转(90%≥SSRI>60%)、显效(60%≥SSRI>20%)、无效(20%≥SSRI≥0%)为标准的四级疗效分级法适用范围较广。结论:慢性荨麻疹临床评估和药物疗效判断标准亟待统一和标准化。
Objective To investigate the criteria for assessing the clinical therapeutic effect of chronic urticaria in China.Methods The application of criteria for assessing the clinical therapeutic effect of chronic urticaria in China and their applicable scope were analyzed by frequency analysis and K-means clustering analysis, respectively.Results The criteria for assessing symptoms and therapeutic effect were different in the 857 papers included in this study. SSRI was used in 549 （64.17） out of the 857 papers included in this study.K-means clustering analysis showed that the applicable scope of SSRI with curative rate （ 100%≥SSRI＆gt;90%） , improvement rate （ 90%≥SSR＆lt;60%） , Significant effect rate （60%≥SSRI＆gt;20%） , and no response rate （20%≥SSR≥0%） as its criteria was wider than that of frequency analysis.Conclusion The criteria for the clinical assessment of chronic urticaria and its drug treatment effect should be unified and standardized.
出处
《中华医学图书情报杂志》
CAS
2014年第12期43-47,共5页
Chinese Journal of Medical Library and Information Science
基金
教育部"春晖计划"合作科研项目(Z2010087)
兰州大学中央高校基本科研业务费项目(lzujbky-2013-116)
兰州大学"国家大学生创新创业训练计划"(201210730080)
关键词
慢性荨麻疹
疗效评估
临床疗效
Chronic urticaria
Therapeutic effect assessment
Clinical curative effect
