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ReCell技术治疗稳定性白癜风的临床疗效 被引量:12

Clinical efficacy of ReCell technique in treatment of stable vitiligo
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摘要 目的探索ReCell技术治疗稳定性白癜风患者的疗效。方法对6例白癜风患者应用ReCell技术治疗,于病变外围切取少量厚度为0.2mm的刃厚皮片,将其置入ReCell试剂盒内酶解后,形成表皮细胞悬液。病变部位应用微型动力系统磨削后,创面喷洒制备的表皮细胞悬液,加压包扎。结果平均随访6个月。5例寻常型白癜风患者出现不同程度的色素恢复,色素恢复面积均〉50%。l例泛发型白癜风患者治疗无效。结论ReCell技术是治疗白癜风的有效外科方法之一。为了获得良好的治疗效果,适应证的选择非常关键。 Objective To evaluate the preliminary outcome of stable vitiligo treatment with Re- Celltechnique. Methods Six patients with stable vitiligo were treated with ReCell technique. In each patient, a thin razor-thickness cutaneous biopsy was harvested from uninvolved area near the viti- ligo patches. It was then processed through the ReCell system and 1 ml autologous epidermal cell suspension was obtained. The lesion area was dermabraded using a diamond fraise wheel to the dermo- epidermal junction. The cell suspension was then sprayed on the wound and covered with non-adhering dressings. Results The patients were followed up for 6 months. 5 patients presented with repigmen- talon in the treated area. There was no significant response in one patient who was diagnosed as sys- tematic vitiligo. Conclusions The ReCell technique is an alternative treatment for stable vitiligo pa- tients. The clinical outcome will be satisfactory when appropriate patients are selected.
出处 《中华医学美学美容杂志》 2014年第6期444-446,共3页 Chinese Journal of Medical Aesthetics and Cosmetology
关键词 ReCell技术 白癜风 外科治疗 ReCell technique Vitiligo Surgical treatment
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  • 1Lu T, Gao T, Wang A, et al. Vitiligo prevalence study in Shaanxi Province, China [J]. Int J Dermatol, 2007,46(1) :47- 51.
  • 2Sandoval-Cruz M, Garcia-Carrasco M, Sdnchez-Porras R, et al. Immunopathogenesis of vitiligo [J]. Autoimmun Rev, 2011,10 (12) :762-765.
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  • 6徐小珂,皇甫晋玲,朱灿,代祖荫,周洁.表皮细胞悬液自体移植治疗节段型白癜风[J].中华医学美学美容杂志,2002,8(1):21-22. 被引量:10
  • 7Cervelli V, De Angelis B, Balzani A, et al. Treatment of stable vitiligo by ReCell system [J]. Acta Dermatovenerol Croat, 2009,17(4) :273-278.
  • 8Mulekar SV, Ghwish B, A1 Issa A, et al. Treatment of vitiligo lesions by ReCellvs. conventional melanocyte-keratinocyte transplantation: a pilot study [J]. Br J Dermatol, 2008, 158 (1) :45-49.

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