期刊文献+

外源性肺泡表面活性物质治疗新生儿呼吸窘迫综合征后胸部X线表现 被引量:5

X-ray manifestations of neonatal respiratory distress syndrome after treatment with exogenous pulmonary surfactant
下载PDF
导出
摘要 目的:探讨新生儿呼吸窘迫综合征(NRDS)患儿在外源性肺泡表面活性物质(PS)治疗前后胸部 X 线表现及其临床应用价值。方法:经临床和影像学检查诊断为 NRDS 的58例患儿使用肺泡表面活性物质进行治疗,分析用药前后患儿的胸部 X 线表现及变化规律。结果:58例患儿首次拍片的诊断结果:NRDS Ⅰ级13例(22%),Ⅱ级25例(43%),Ⅲ级13例(22%),Ⅳ级7例(13%);PS 治疗后2~72 h 第1次复查胸片,示双肺透亮度较前增高48例,降低5例,增高且伴有纵隔和(或)肺间质积气4例;19例进行第2次复查胸片,显示双肺内恢复正常3例,新生儿肺炎15例,新生儿肺炎并纵隔、肺间质积气1例;11例第3次复查胸片,显示双肺内恢复正常3例,肺炎7例,新生儿肺炎并纵隔、间质积气1例;1例第4次复查胸片,示支气管肺发育不良。胸片显示气管插管位置异常10例。结论:X 线检查可用于评价外源性肺泡表面活性物质治疗 NRDS 的疗效,了解气管插管的位置,并能早期发现肺炎、纵隔和肺间质积气等并发症。 Objectire:To investigate X-ray findings of neonatal respiratory distress syndrome (NRDS)before and af-ter treatment with exogenous pulmonary surfactant (EPS)and its clinical value.Methods:58 patients with neonatal respira-tory distress syndrome treated with exogenous pulmonary surfactant were diagnosed by clinical and radiology,the X-ray findings and changes on chest film before and after treatment were analyzed retrospectively.Results:Before treatment,the results of the first X-ray film in 58 cases:NRDS grade Ⅰ in 13 cases (22%),NRDS grade Ⅱ in 25 cases (43%),NRDS grade Ⅲ in 13 cases (22%),NRDS grade Ⅳ in 7 cases (13%).All cases underwent the first X-ray reexamination 2 ~72 hours after treatment,the transparency of lung increased in 48 cases,decreased in 5 cases,increased with pneumomediasti-num and pulmonary interstitial pneumatosis in 4 cases.19 cases underwent the second X-ray reexamination,the lung was showed normal in 3 cases,pneumonia in 15 cases,pulmonary interstitial pneumatosis in 1 case.On the chest film of the third follow-up examination,the lung had normal findings in 3 cases,pneumonia in 7 cases,pulmonary interstitial pneumatosis in 1 case.Only one case underwent the fourth follow-up examination,and showed bronchopulmonary dysplasia.Abnormal posi-tion of endotracheal intubation was showed in 10 cases.Conclusion:X-ray examination is helpful not only to evaluation of the treatment effect of EPS for NRDS,and the position of endotracheal intubation,but also to early detection of the compli-cations including pneumonia,pneumomediastinum and pulmonary interstitial emphysema.
作者 陈荟竹 宁刚
出处 《放射学实践》 2014年第12期1415-1419,共5页 Radiologic Practice
关键词 新生儿 呼吸窘迫综合征 肺泡表面活性物质 放射摄影术 Neonate Neonatal respiratory distress syndrome Pulmonary surfactant Radiology
  • 相关文献

参考文献14

二级参考文献65

  • 1王莹,马雅玲,张巍.肺表面活性物质预防早产儿RDS的临床观察[J].新生儿科杂志,2004,19(4):148-151. 被引量:27
  • 2甘小庄,宋国维.欧洲和加拿大肺表面活性物质临床应用指南和建议[J].新生儿科杂志,2005,20(4):189-192. 被引量:33
  • 3叶鸿瑁,黎晓新.早产儿治疗用氧和视网膜病变防治指南[J].中华围产医学杂志,2006,9(6):363-364. 被引量:54
  • 4常立文.新生儿支气管肺发育不良诊治进展[J].临床儿科杂志,2007,25(3):161-165. 被引量:46
  • 5崔祥璸,王鸣歧,萨藤三.实用肺脏病学[M].上海:上海科学技术出版社,1991,12:199-203.
  • 6Hack M,Wright LL, Shankaran S, et al. Very-low-birth-weight outcomes of the National Institute of Child Health and Human Development Neonatal Network,November 1989 to October 1990; Am J Obstet Gynecol, 1995,172:457-464.
  • 7Qian L, Liu C, Zhuang W ,et al. Neonatal respiratory failure:a 12-month clinical epidemiologic study from 2004 to 2005 in China. Pediatrics, 2008,121 : 1115-1124.
  • 8Gouyon JB, Ribakovsky C, Ferdynus C, et al. Severe respiratory disorders in term neonates. Paediatr Perinat Epidemiol,2008 ,22 :22-30.
  • 9Raju TN,Higgins RD,Stark AR,et al. Optimizing care and outcome for late-preterm (near-term) infants: a summary of the workshop sponsored by the National Institute of Child Health and Human Development. Pediatrics,2006,118 : 1207-1214.
  • 10Baroutis G, Kaleyias J, Liarou T, et al. Comparison of three treatment reg- imens of natural surfactant preparations in neonatal respiratory distress syndrome. Eur J Pediatr,2004,163:476-480.

共引文献71

同被引文献53

引证文献5

二级引证文献38

相关作者

内容加载中请稍等...

相关机构

内容加载中请稍等...

相关主题

内容加载中请稍等...

浏览历史

内容加载中请稍等...
;
使用帮助 返回顶部