摘要
目的了解新疆地区血液感染的主要病原菌及耐药情况。方法 4 534例血液标本采用BACT-ALERT 3D全自动血培养仪进行细菌培养,细菌培养阳性标本采用梅里埃公司的Vitek-TWO系统行菌种鉴定和药敏试验。结果 4 534例血液细菌培养标本中,离出病原菌359株株,阳性率为7.92%,其中革兰阳性菌占53.5%,革兰阴性菌占43.4%,真菌占3.1%。61.9%的金黄色葡萄球菌耐苯唑西林,产ESBLs的大肠埃希菌为60%,产ESBLs的肺炎克雷伯菌为44.4%,未见耐万古霉素的革兰阳性菌。结论新疆地区引起血液感染的主要病原菌以革兰阳性菌为主,耐药菌株广泛出现,及时了解血培养结果,选用敏感药物针对性用药,可有效提高菌血症的治愈率。
Objective To explore the pathogen distribution charaterstics and drug resistance of blood culture in Xinjiang. Meth- ods BACT-ALERT 3D automated blood culture system was used to cuture the 4 534 blood samples,the Vitek-TWO BioMerieux system were used in the identification and susceptibility testing of positive samples species. Results A total of 359 strains were iso- lated from 4 534 blood samples, the positive rate of 7.92 %. Gram-positive cocci accounted for 53.5 %, gram-negative bacteria ac- counted for 43.4 %, fungi accounted for 3.1%. 61.9 % strains was methicillin-resistant. Escherichia cull and Klebsiella β-super-lactamases were 60 % and 44.4 % respectively, no vancomycin-resistant mold elements of the gram-positive cocci was found. Conclusion The main hospital pathogens causing blood culture infections is gram-positive bacteria, the drug resistant bacteria is still wide- spread,keeping abreast of the blood culture results,choosing sensitive drugs could improve the cure rate of bacteremia.
出处
《国际检验医学杂志》
CAS
2015年第2期159-160,162,共3页
International Journal of Laboratory Medicine
基金
新疆维吾尔自治区病原生物学重点学科项目(2013ZRQN35)
关键词
血液培养
病原菌的分布
耐药性
blood culture
pathogen distribution
drug resistance
