摘要
瘙痒是皮肤科的一种常见症状,是多因素相互作用的结果,其发生受到中枢和外周机制的双重调控,但具体发生机制尚不十分清楚。近年来随着研究的不断深入,多种物质如组胺、乙酰胆碱、5-羟色胺、蛋白酶和蛋白酶相关受体、细胞因子、阿片样肽等介质在瘙痒产生过程中起重要作用,这些介质通过刺激C类神经纤维或直接与皮肤感觉神经纤维受体相结合来介导瘙痒。本文就将皮肤瘙痒的神经传导及传导介质作一综述。
Objective：Itching is a common symptom of dermatology, is the result of the interaction of multiple factors, which by the central and peripheral mechanisms of dual control occur, but the exact mechanism is not clear.With the deepening of research in recent years, a variety of substances such as histamine, acetylcholine, serotonin, proteases and protease-related receptors, cytokines, opioid peptides, and other media play an important role in the generation process of pruritus, these media by stimulating type C nerve fibers or nerve fibers directly mediate receptor binding and skin feel itchy. Nerve conduction and conduction article will pruritus medium reviewed.
出处
《中国医学创新》
CAS
2015年第2期150-153,共4页
Medical Innovation of China
关键词
瘙痒
神经传导介质
综述
Itching Nerve conduction medium Progress
