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脑心清片对冠心病心绞痛患者PCI术后的安全性及VEGF,hs-CRP的影响 被引量:2

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摘要 目的探讨脑心清片对冠心病患者PCI术后的安全性及VEGF,hs-CRP的影响。方法将在该院接受治疗的冠心病心绞痛并行PCI术后84例患者随机均分成治疗组和对照组,两组均给予常规药物治疗,治疗组在此基础上服用脑心清片,治疗8周后,比较两组心绞痛疗效、不良心血管事件以及血清VEGF和hs-CRP水平。结果两组VEGF以及hs-CRP水平较治疗前相比均明显下降(P<0.05);治疗组心绞痛疗效显著高于对照组(P<0.05);两组不良心血管事件发生率相互比较差异无统计学意义。结论脑心清片对冠心病患者PCI术后有较好的临床疗效,其作用机理可能与降低VEGF,hs-CRP的表达水平有关。
出处 《中外医疗》 2014年第30期138-139,共2页 China & Foreign Medical Treatment
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  • 1King SB 3rd, Smith SC Jr, Hirshfeld JW Jr, et al. 2007 Focused update of the ACC/AHA/SCAI 2005 Guideline Update for Percutaneous Coronmy Intervention: A Report of the American College of Cardiology/American Heart Association task force on practice guidelines: 2007 writing group to review new evidence and update the ACC/AHA/SCAI 2005 guideline update for pereutaneous coronary intervention, writing on behalf of the 2005 writing committee [J]. Circulation, 2008, 117(2) : 261-295.
  • 2Lee JY, Park DW, Yun SC, et al. Long-term clinical outcomes of Sirolimus- versus Paclitaxel-eluting stents for patients with unprotected left main coronary artery disease: Analysis of the MAIN-COMPARE (Revascularization for unprotected left main coronary artery stenosis: Comparison of percutaneous coronary angioplasty versus surgical revascularization) registry [J]. J Am Coil Cardiol, 2009,54 (9) :853-859.
  • 3Daemen J, Kukreja N, Serruys PW. Drug-eluting stents vs.coronary-artery bypass grafting[J]. N Engl J Med, 2008,358 ( 24 ) : 2641-2644.
  • 4Daemen J, Boersma E, Flather M, et al. Long-term safety and efficacy of percutaneous coronary intervention with stenting and coronary artery bypass surgery for multivessel coronary artery disease: A meta-analysis with 5-year patient-level data from the ARTS, ERACI-II, MASS-II, and SoS trials [J]. Circulation, 2008,118(11): 1146-1154.
  • 5Booth J, Clayton T, Pepper J, et al. SoS Investigators. randomized, controlled trial of coronary artery bypass surgery versus percutaneous coronary intervention in patients with multivessel coronary artery disease: Six-year follow-up from the Stent or Surgery Trial (SOS) [J]. Circulation, 2008,118(4): 381-388.
  • 6Sianos G, Morel MA, Kappetein AP, et al. The SYNTAX score: An angiographic tool grading the complexity of coronary artery disease [ J ]. EuroIntervention, 2005,1 (2) : 219-227.
  • 7Nashef SAM, Roques F, Michel P, et al. The EuroSCORE study group. European System for Cardiac Operative Risk Evaluation (EuroSCORE) [J]. Eur J Cardiothorac Surg, 1999, 16(1):9-13.
  • 8Parsonnet V, Dean D, Bernstein AD. A method of uniform stratification of risk for evaluating the results of surgery in acquired adult heart disease [J]. Circulation, 1989,79(6 Pt 2) :13-12.
  • 9中华人民共和国卫生部.中药新药临床研究指导原则[S].北京:中国医药科技出版社,2002.68-74.
  • 10US Departmentof Healthand Human Services Monograph,1996年,30页

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