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泽漆脂溶性成分的气相色谱-质谱联用分析 被引量:1

GC-MS Analysis of Liposoluble Contents from Euphorbia helioscopia L.
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摘要 目的对泽漆脂溶性成分进行研究。方法将泽漆用95%乙醇渗漉提取后再用石油醚萃取得到脂溶性成分,用气相色谱-质谱联用仪(GC-MS)对其进行分析和鉴定。结果从泽漆中共分离鉴定出24种成分,占流出峰总面积的87.93%。主要成分依次为24-亚甲基环木菠萝烷醇(21.84%)、棕榈酸(15.79%)、羽扇豆醇(10.91%)、乙酸羽扇醇酯(10.51%)、棕榈酸乙酯(7.35%)、羽扇烯酮(4.20%)和β-谷甾醇(3.14%)。结论为进一步探讨泽漆药理作用及合理利用该植物资源提供了科学依据。 Objective To analyze the chemical constituents of the liposoluble contents from Euphorbia helioscopia L. Methods The liposoluble contents from Euphorbia helioscopia L. were extracted by petroleum ether and then analyzed by GC - MS. Results 24 compounds were separated, identified and accounted for 87.93% of the total compounds. The major chemical constituents were 24 - methylenecyeloartanol 21.84% , hexadeeanoie acid 15.79% , lupeol 10.91%, lupeol acetate 10.51% , hexadeeanoic acid, ethyl ester 7.35% , lupenone 4.20% and β - sitosterol 3.14%. Conclusion The results will provide founda- tion for further exploitation and use of Euphorbia helioscopia L.
出处 《时珍国医国药》 CAS CSCD 北大核心 2015年第1期9-10,共2页 Lishizhen Medicine and Materia Medica Research
基金 国家海洋"863"计划(No.2013AA092902) 国家自然科学基金(No.81273430 No.31070310) 中科院上海药物研究所新药研究国家重点实验室项目(No.SIMM1203ZZ-03)
关键词 泽漆 脂溶性成分 气相色谱-质谱联用 Euphorbia helioscopia L. Liposoluble contents GC -MS
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  • 1Goad L J, Goodwin T W. The biosynthesis of sterols in higher plants [J]. BiochemJ, 1966, 99(3):735.
  • 2曾佑玲,吉庆发,易琼,郭庆,何炳坤,王鲁.向日葵叶抗氧化成分24-亚甲基环木菠萝烷醇的分离提取[J].中兽医医药杂志,2010,29(2):40-41. 被引量:8
  • 3刘睿,顾谦群,崔承彬,韩冰,蔡兵,刘红兵.密脉鹅掌柴的化学成分及其抗肿瘤活性[J].中草药,2005,36(3):328-332. 被引量:53
  • 4Saleem M, Kaur S, Kweon M H, et al. Lupeol, a fruit and vegetable based triterpene, induces apoptotic death of human pancreatic adeno- carcinoma cells via inhibition of Ras signaling pathway [ J ]. Carcino- genesis, 2005, 26( 11 ) : 1956.
  • 5Gallo M B C, Sarachinc M J. Biological activities of lupeol [ J 1. Int J Biomed Pharm Sci, 2009, 3 ( Special Issue I ) : 44.
  • 6Lee T K, Castilho A, Cheung V C, et al. Lupeol targets liver tumor - initiating cells through phosphatase and tensin homolog modulation[ J 1. Hepatology, 2011, 53( 1 ): 160.
  • 7Nitta M, Azuma K, Hata K, et al. Systemic and local injections of lu- peol inhibit tumor growth in a melanoma bearing mouse model[ J]. Bi- omed Prep, 2013, 1(4): 641.
  • 8Gupta M B, Nath R, Srivastava N, et al. Anti - inflammatory and anti- pyretic activities of 13 - sitosterol [ J ]. Planta medica, 1980, 39 (6) : 157.

二级参考文献16

  • 1吴琦,杨秀伟,杨世海,邹磊,阎静.金毛狗脊的化学成分研究[J].天然产物研究与开发,2007,19(2):240-243. 被引量:23
  • 2Oyaizu M.Studies on products of browning reaction:antioxidative reaction prepared from glucosamine[J].Jpn J Nutr,1986,44:307.
  • 3Goad L J,Goodwin T W.The biosynthesis of Sterols in higher Plants[J].Biochem J,1966,99:735.
  • 4XieZW.全国中草药汇编[M]. Vol 2[M].Beijing: People''s Medical Publishing House,1996..
  • 5Cui C B, Yan S Y, Cai B, et al. Carbazole alkaloids as new cell cycle inhibitors and apoptosis inducers from Clausena Dunniana Levi [J]. J Asian Nat Prod Res, 2002, 4(4):233-241.
  • 6Cui C B, Zhao Q C, Cai B, et al. Two new and four knownpoly phenolics obtained as new cell-cycle inhibitors from Rubus aleaefolius Poin [J]. J Asian Nat Prod Res, 2002, 4(4) : 243-252.
  • 7Purohit M C, Pant G, Rawat M S M. A beulinic acid glycoside from Schefflera venulosa [J]. Phytochemistry, 1991, 30(7) : 2419.
  • 8Purohit M C, Rawat M S M, Pant G. Spermicidal activity and chemical analysis of Schefflera venulosa [J]. Fitoterapia, 1993, 64(3): 274-272.
  • 9Natro G, Piccialli V, Sica D. New steroidal hydroxyketones and closely related diols from the marine sponge Cliona copiosa [J]. J Nat Prod, 1992, 55: 1588-1594.
  • 10Fei X N, Zhang T Y, Zhou C L. Modification study involviing naphthol as red pigment [J]. Dyest Pigment, 2000, 44(2):75-80.

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