摘要
目的:分析比较绿激光汽化术与经尿道膀胱肿瘤切除术(TURBT)治疗非肌层浸润性膀胱癌的临床治疗效果。方法:选取我院102例非肌层浸润性膀胱癌患者为研究对象,根据知情自愿原则选择两种不同手术,行激光汽化术的52例患者设为观察组,行TURBT的50例患者设为对照组。分析比较两组患者的手术耗时、出血量、尿管置留时间、肉眼血尿时间、住院时间及并发症情况,并分析影响复发的危险因素。结果:观察组的手术耗时及术中出血量与对照组比较均无显著性差异(P>0.05),而尿管保留时间、血尿时间及住院时间短于对照组,差异具有统计学意义(P<0.05);观察组并发症发生率显著小于对照组(P<0.05);较大肿瘤与较高的病理分级有高复发风险,而肿瘤数目和不同手术方式(绿激光/TURBT)与膀胱癌术后复发无显著相关性(P>0.05)。结论:绿激光汽化术对非肌层浸润性膀胱癌具有较好的治疗效果,与TURBT比较可缩短尿管保留、血尿及住院时间,且明显降低并发症发生率,但两种手术方式对复发率的影响差异不大。
Objective：To compare the efficacy and safety of green laser vaporization with transurethral resection（ TURBT） for the treatment of non-muscle-invasive bladder cancer （ NMIBC） . Method：102 pa-tients suffered non-muscle-invasive bladder cancer were divided into observation group （ 52 cases） and the control group （50 cases） according to the principle of voluntary and informed. The former were treated with green laser vaporization surgery while the later with TURBT. Operation time,blood loss, catheter indwelling time, gross hematuria, hospitalization time and complications of patients were recorded. Risk factors for recur-rence were analyzed. Result：Two groups of operation time and blood loss had no significantly difference（ P〉0. 05） ,but catheter indwelling time, gross hematuria, hospitalization time and complications of observation group were obviously less than those of control group（ P〈0. 05）. Larger tumors and higher tumor grade with a high risk of recurrence. While there＇s no significant correlation between the number of tumors, different surgi-cal methods （ green laser / TURBT） and bladder cancer recurrence. Conclusion：The green laser vaporiza-tion surgery for treatment of NMIBC has a better therapeutic effect and a low complication rate. Catheter in-dwelling time, gross hematuria and hospitalization time can be shortened compared with TURBT. But there＇s litter difference in the impact of the two surgical to recurrence rate.
出处
《河北医学》
CAS
2015年第2期177-179,共3页
Hebei Medicine
基金
国家自然科学基金
(编号:81300624)
