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甘精胰岛素联合瑞格列奈治疗2型糖尿病临床疗效 被引量:5

The clinical analysis of insulin glargine combined repaglinide in treatment of type 2 diabetes
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摘要 目的探讨甘精胰岛素联合瑞格列奈治疗2型糖尿病临床疗效。方法回顾性分析2010年1月至2014年1月我院收治的160例2型糖尿病患者的临床资料。结果两组患者治疗后的FPG、PPG、Hb A1c水平与同组治疗前比较明显降低,P<0.05,差异具有统计学意义;观察组治疗后的FPG、PPG水平与对照组比较,P>0.05,无明显差异性;观察组治疗后的Hb A1c水平与对照组比较,明显降低,P<0.05,差异具有统计学意义。观察组患者经甘精胰岛素联合瑞格列奈治疗,低血糖发生率及日胰岛素用量明显低于对照组,经比较,P<0.05,差异具有统计学意义。结论甘精胰岛素联合瑞格列奈治疗2型糖尿病,不仅可以较好地控制血糖水平,还可以降低低血糖事件的发生几率,减少胰岛素用量,且每日一次皮下注射,更易为患者接受,值得临床推广应用。 [Objective]to investigate the insulin associated ziggy nai clinical efficacy in the treatment of type 2 diabetes.Methods: a retrospective analysis in January 2010 to January 2014,our hospital of the clinical data of 160 cases of patients with type 2 diabetes. Results: two groups of patients after treatment of FPG,PPG,HbA 1c level significantly lower compared with the same group before treatment,P 0. 05,the difference is statistically significant; Observation group after treatment of FPG,PPG level compared with control group,P 0. 05,no significant difference;HbA 1c level of observation group after treatment compared with control group,significantly decreased,P 0. 05,the difference is statistically significant. Observation group of patients with insulin associated ziggy nai treatment,incidence of hypoglycemia and insulin dosage significantly lower than the control group,by comparison,P 0. 05,the difference is statistically significant. Conclusion: insulin joint nai raigor column treatment of type 2 diabetes,can not only better control blood sugar levels,can also reduce the risk of hypoglycemic events,reduce the dosage of insulin,and subcutaneous injection once a day,easier for patients to accept,worthy of clinical popularization and application.
作者 毛军
出处 《工企医刊》 2014年第6期1081-1082,共2页 The Medical Journal of Industrial Enterprise
关键词 甘精胰岛素 瑞格列奈 2型糖尿病 insulin Glenn nai.Type 2 diabetes
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