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57例三阴性乳腺癌的临床病理特征分析 被引量:1

Clinicopathological Features of 57 Patients with Triple Negative Breast Cancer
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摘要 目的探讨三阴性乳腺癌(TNBC)的临床病理特征。方法回顾性分析57例TNBC患者的临床资料,并以280例非三阴性乳腺癌患者(NTNBC)作为对照。结果 TNBC组Ⅲ级28例(49.1%),NTNBC组12例(4.3%)(P<0.05)。局部复发率在TNBC组及NTNBC组中分别为15.8%及6.8%(P<0.05);远处转移率分别为26.3%及14.6%(P<0.05)。结论乳腺癌TNM分期能够反映TNBC的侵袭性和复发转移的临床特点,TNBC患者更易出现淋巴结转移及远处转移。 Objective To analyze the clinicopathological features of the patients with triple negative breast canc-er. Methods The data of 57 patients with triple negative breast cancer( TNBC)were analyzed retrospectively,and the 280 patients with non-triple negative breast cancer( NTNBC)were the control group. Results The patients with grade Ⅲ were 28 patients(49. 1%)in the TNBC group,and were 12 patients(4. 3%)in the NTNBC group (P〈0. 05). The local recurrence rate was 15. 8% in the TNBC group,and was 6. 8% in the NTNBC group(P〈0. 05);the metastasis rate was 26. 3% and 14. 6%,retrospectively(P〈0. 05). Conclusion The TNM staging system for breast cancer can reflect the features of invasion,recurrence and metastasis of TNBC,TNBC has the high metastasis rate.
作者 孙艳霞
出处 《肿瘤基础与临床》 2014年第6期512-513,共2页 journal of basic and clinical oncology
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  • 1赵卫红,徐兵河,张频,李青,赵龙妹,孙燕.乳腺癌合并脉管瘤栓的临床病理特点及预后因素分析[J].中华肿瘤杂志,2007,29(2):137-140. 被引量:14
  • 2Carey LA, Perou CM, Livasy CA, et al. Race, breast cancer subtypes, and survival in the Carolina Breast Cancer Study. JAMA, 2006, 295:2492-2502.
  • 3Carlson RW, Moench SJ, Hammond ME, et al. HER2 testing in breast cancer: NCCN Task Force report and recoannendations. J Natl Compr Canc Netw, 2006, 4 Suppl 3 :S1-22.
  • 4Cleator S, Heller W, Coombes RC. Triple-negative breast cancer: therapeutic options. Lancet Oncol, 2007, 8:235-244.
  • 5Rakha EA, El-Sayed ME, Green AR, et al. Prognostic markers in triple-negative breast cancer. Cancer, 2007, 109:25-32.
  • 6Perez EA, Roche PC, Jenkins RB, et al. HER2 testing in patients with breast cancer: poor correlation between weak positivity by immunohistochemistry and gene amplification by fluorescence in situ hybridization. Mayo Clin Proc, 2002, 77:148-154.
  • 7Kandel MJ, Stadler Z, Masciari S, et al. Prevalence of BRCA1 mutations in triple negative breast cancer (BC). Proc Am Soc Clin Oncol, 2006, 24 :abstr 508.
  • 8Herr A, Gluz O, Ting E, et al. Biological characteristics in triple negative high risk breast cancer and their clinical implications. Proc Am Soc Clin Oncol, 2006, 24 : abstr 20032.
  • 9Livasy CA, Karaca G, Nanda R, et al. Phenotypic evaluation of the basal-like subtype of invasive breast carcinoma. Mod Pathol, 2006, 19:264-271.
  • 10Banerjee S, Reis-Fliho JS, Ashley S, et al. Basal-like breast carcinomas: clinical outcome and response to chemotherapy. J Clin Pathol, 2006, 57:729-735.

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