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Wnt/β-catenin信号通路与骨性关节炎的形成机制 被引量：6

Wnt / β-catenin Signal Access and Formation Mechanism of Osteoarthritis
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摘要 Wnt信号通路通过对胚胎期软骨的发育和出生后软骨的发生、成骨细胞以及破骨细胞的生成、骨折修复等过程进行调节,而起到调节骨系统疾病和骨代谢的作用。Wnt/B-catenin通路与骨关节炎有着紧密的联系,且Wnt/B-catenin通路同时也是维持关节软骨的稳定的重要因素。 Wnt signal access has the functions of regulating bony system diseases and bony metabolism by adjusting chondral growth during embryo period, chondral development after birth, formation of osteoblast and ostoeclast, fracture recovery and healing. There is a close relationship between Wnt/β-catenin access and osteoarthritis. What＇ s more, Wnt/β-catenin access is an important factor which keeps joints chondral stability.
作者 董旺超
机构地区 南京市中医院
出处 《河南中医》 2015年第1期81-83,共3页 Henan Traditional Chinese Medicine
基金 江苏省中医药局科技发展项目(编号:LB09083)
关键词 骨性关节炎 Wnt信号通路 Wnt/β-连环蛋白 Wnt细胞外信号 MMP OPG/RANK/RANK osteoarthritis Wnt signal access Wnt/β-concatemeric protein Wnt signal outside cell MMP OPG/RANK/RANK
分类号 R274.984.3 [医药卫生—中西医结合]
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河南中医
2015年 第1期

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