摘要
进入二十一世纪,随着新研究方法的涌现和学科之间的交叉融合,现代流行病学取得了长足的发展和进步。近期研究表明,一些慢性病的发生和发展难以用成年期的暴露状态来完全解释。综合的、动态的生命历程研究框架的提出,为探索疾病、尤其是慢性疾病的病因,提供了一个新的平台。生命历程流行病学整合了成人生活方式模型与胎生起源学说,并将其扩展到生物学、社会心理学和社会学等领域中,以促进个人和群体远期健康水平。本文对生命历程流行病学的定义、理论模型和研究方法,以及它在慢性病研究方面的应用进行了综述,并对生命历程流行病学的发展进行了展望。
Converging with other related discipline and new methods, modern epidemiology has made considerable progress since the 21st century. However, published literature cannot sufficiently support the causal relationships between adult exposures and outcomes. The comprehensive and dynamic life course framework can provide a fresh perspective on in- vestigating the causes, especially the aetiology of chronic diseases. Life course epidemiology, which attempts to integrate the traditional adult lifestyle model and fetal origin hypothesis, has expanded to many fields such as biology, social psychol- ogy and sociology in order to improve the long term health of individuals and social groups. This review aims to introduce the definition, theoretical models and research methods of life course epidemiology and to discuss its application to chronic diseases. The outlook of life course epidemiology is also discussed.
出处
《中华疾病控制杂志》
CAS
CSCD
北大核心
2015年第2期196-199,共4页
Chinese Journal of Disease Control & Prevention
基金
首都医科大学基础-临床科研合作基金(13JL85)
关键词
流行病学
慢性病
综述
Epidemiology
Chronic disease
Review
