摘要
目的了解降钙素原在重症肺炎中的诊断价值。方法 46例重症肺炎患者为实验组,另选取同期体查的46例健康体检者为对照组,均于1 d内行血常规、C-反应蛋白、降钙素原、体温测定,并从血清降钙素原水平出发,将实验组进行分级（包括≥10.0μg/L组、〈0.5μg/L组、≥2.0~10.0μg/L组、≥0.5~2.0μg/L组）,观察各组呼吸机应用状况、病死情况及住院时间与抗生素使用时间。结果实验组C-反应蛋白、降钙素原显著高于对照组（P〈0.05）,中性粒细胞百分比、白细胞计数、体温对比差异无统计学意义（P〉0.05）;降钙素原水平与重症肺炎患者住院时间、呼吸机应用次数、抗生素使用时间具有相关性（P〈0.05）。结论降钙素原在重症肺炎临床诊断与病情评估中具有重要的指导价值,在临床上应引起足够重视。
Objective To understand the diagnostic value of procalcitonin in severe pneumonia. Methods A total of 46 severe pneumonia patients were selected as experimental group, and 46 healthy people at the same period were Chosen as control： group. They all received blood routine examination, detection of C-reactive protein, procalcitonin, and body temperature within 1 d. The experimental group was classified by procalcitonin level （as ≥ 10.0 μo/L group, 〈0.5 μg/L group,≥ 2.0--10.0 μg/L group, and ≥ 0.5~2.0 μg/L group）. Application of breathing machine, fatality state, hospital stays, and antibiotics use time were observed in all the groups. Results The experimental group had obviously higher levels of C-reactive protein and procalcitonin than the control group （P〈0.05）. The differences of neutrophile granulocyte percentage, white blood cell count, and body temperature had no statistical significance （P〉0.05）. The level of procalcitonin had a correlhtion with hospital stays, application times of breathing machine, and antibiotics use times of the severe pneumonia patients （P〈0.05）. Conclusion Procalcitonin has important guiding value in clinical diagnosis and disease assessment of severe pneumonia, and it ought to be paid with enough attention in clinic.
出处
《中国现代药物应用》
2015年第5期3-5,共3页
Chinese Journal of Modern Drug Application
关键词
降钙素原
重症肺炎
应用价值
Procalcitonin
Severe pneumonia
Application value
