摘要
目的:通过观察分析依托咪酯和丙泊酚联合瑞芬太尼应用于剖宫产全麻诱导,比较两种方法对产妇及新生儿的影响。方法:选择近3年来我院60例拟行剖宫产手术产妇,分为两组:依托咪酯组(B组)、丙泊酚组(C组),每组30例。记录产妇不同时间点(诱导前、插管后、胎儿娩出时、胎儿娩出后10min)血流动力学改变、麻醉诱导至胎儿娩出时间、术中知晓及术后恶心呕吐等不良反应发生率及新生儿Apgar评分。结果:B、C两组产妇及新生儿均未出现严重的不良反应。B组插管后HR、BP变化高于C组(P<0.05),其余时间点差异无统计学意义;B组术后恶心、呕吐发生率高于C组(P<0.05);B组新生儿1min和2min Apgar评分高于C组(P<0.05),2min以后两组间差异无统计学意义。两组胎儿娩出时间差异无统计学意义。结论:丙泊酚及依托咪酯联合瑞芬太尼均可安全用于剖宫产全麻诱导。
Objective： In this article, by observing and analyzing Etomidate or Propofol combined Remifentanil applied to Induction of general anesthesia in Cesarean Section, we compared the effect on the mother and newborn by using the above-mentioned two methods. Methods： Selected 60 patients in our hospital with 3 years scheduled for cesarean section parturients operation, and divided them into two groups： Etomidate group（B group）, Propofol group（C group）, 30 cases in each group. Recoded at different time points （before induction, after tracheal intubation, fetus, 10rain after fetal childbirth） the changes of hemodynamics, anesthesia awareness and postoperative induction to delivery interval, in traoperative adverse reaction such as nausea and vomiting and neonatal Apgar score. Results：There was no serious adverse effects of the mothers and newborns in B group and C group. After tracheal intubation, the changes of HR and BP are higher than C group（P〈0. 05）. There is no statistically significant differences in the rest of the time points. The rate of Postoperative nausea and vomiting incidence in B group is higher than that in C group（P〈0. 05）. The Apgar scores in lmin and 2min of B group are higher than C group（P〈0. 05）, and there is no statistically significant differences after 2min. There is no statistically significant differences between two groups of fetal disengagement time. Conclusion.. Etomidate or Propofol combined Remifentanil are both applied to Induction of general anesthesia in Cesarean Section safely.
出处
《医学理论与实践》
2015年第3期307-308,315,共3页
The Journal of Medical Theory and Practice
关键词
全麻
新生儿
剖宫产
General anesthesia,Newborns, Cesarean section
