摘要
达玛烷-3β,12β,20,25-四醇(25-OH-PPD)是人参的有效活性成分之一,为了进一步研究和利用该有效成分,本文对25-OH-PPD及其衍生物的化学性质、抗癌活性及其构效关系的研究进行综述。
As an active component of ginseng, 20 （R） -dammarane-3β, 12β, 20,25-tetrol （ 25-OH-PPD ） has been demonstrated that can inhibit the growth and proliferation or induce differentiation and apoptosis of tumor cells. This article mainly summarizes the research advances of 25-OH-PPD and its derivatives in recent years,including chemical properties, anticancer activities and structure-activity relationships, which provides information for the research and development of 25-OH-PPD.
出处
《中国药物化学杂志》
CAS
CSCD
2015年第1期66-73,共8页
Chinese Journal of Medicinal Chemistry
基金
国家自然科学基金项目(81273389)
