摘要
目的观察川崎病治疗前后血清降钙素原的变化并探讨其意义。方法回顾性总结在中日友好医院接受大剂量丙种球蛋白治疗的53例川崎病患儿资料,分析大剂量丙种球蛋白治疗前后血清降钙素原(PCT)的变化特点,同时分析C反应蛋白(CRP)、红细胞沉降率(ESR)及血常规白细胞计数(WBC)的变化情况。结果入组川崎病患儿共53例,其中男28例,女25例;发病年龄3个月到9岁,治疗后患儿PCT较治疗前明显下降(P<0.05),两者相比有统计学意义,CRP较治疗前明显下降(P<0.01),ESR和WBC的变化差异无统计学意义(P>0.05)。结论血清降钙素原在川崎病治疗前后变化明显,可作为监测川崎病病情变化的一个重要指标。
Objective To investigate the changes and clinical significance of serum procalcitonin（PCT） level in children with Kawasa- ki disease（KD）. Methods The clinical data and laboratory findings of 53 children with KD who were treated with high dosage of in- travenous immune globulin（IVIG） were analyzed retrospectively. The alterations of PCT, C reaction protein （CRP）, erythrocyte sedi- mentation rate（ESR） and white blood cell counting（WBC） were detected before and after treatment. Results Of 53 children with KD, there was 28 boys and 25 girls, and the age ranged from 3 months to 9 years. The serum PCT level significantly decreased after treatment（P 〈 0.05 ）. The CRP level also decreased significantly（P 〈0.01 ）. But ESR and WBC had no statistical change. Conclu- sion Serum PCT could be used to monitor the clinical conditions of KD.
出处
《山西医科大学学报》
CAS
2015年第2期179-180,共2页
Journal of Shanxi Medical University
关键词
川崎病
降钙素原
C反应蛋白
Kawasaki disease
procalcitonin
C reaction protein
