摘要
目的研究组织因子(TF)和P-选择素的检测在AECOPD中的临床诊断价值。方法对100例AECOPD患者、100例慢阻肺患者和100例健康体检人员进行TF和P-选择素水平的检测,分析比较在不同组中TF和P-选择素的水平。结果 AECOPD患者体内TF和P-选择素水平均高于慢阻肺对照组和健康对照组,有显著性差异(P<0.05);慢阻肺对照组体内TF水平稍微高于健康对照组,但无显著性差异(P>0.05);慢阻肺对照组体内P-选择素水平仍高于健康对照组,有显著性差异(P<0.05)。结论 TF和P-选择素水平的检测对AECOPD的诊断具有重要意义,有助于了解患者病程和预后情况。
Objective To investigate the clinical significance of tissue factor （TF） and P-selectin detection in the diagnosis of AECOPD. Methods 100 patients with AECOPD, 100 patients with COPD and 100 healthy con- trols were recruited to detect the levels of TF and P-selectin, and the levels of TF and P-selectin in the three groups were compared and analyzed. Results In the AECOPD group, the levels of TF and P-se｜ectin were higher than those in the COPD group and the healthy control group （P 〈 0. 05）. The level of TF in the COPD group was slightly higher than that in the healthy control group （P 〉 0.05）. The level of P-selectin in the COPD group was also higher than that in the healthy control group （ P 〈 0.05 ）. Conclusion The detection of TF and P-selectin levels shows great sig- nificance for the diagnosis of AECOPD patients.
出处
《临床肺科杂志》
2015年第3期523-525,共3页
Journal of Clinical Pulmonary Medicine
关键词
慢性阻塞性肺疾病
组织因子
P-选择素
chronic obstructive pulmonary disease tissue factor P-selectin
