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准分子激光术治疗大泡性角膜病变的疗效及安全性 被引量:3

Analysis of clinical efficacy and safety of excimer laser technology in the treatment of bullous keratopathy
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摘要 目的:探讨准分子激光治疗性角膜切削术(PTK)在治疗大泡性角膜病变(BK)中的临床疗效及安全性。方法:回顾性分析了2011-10/2014-07于我院眼科接受诊疗的BK患者60例60眼的临床资料,采用PTK术对其进行治疗。比较手术前后最佳矫正视力(BCVA)、角膜曲率、角膜散光度数、角膜厚度及角膜内皮细胞密度(ECD)、术后并发症发生情况。结果:本组患者术前BCVA、角膜曲率、角膜散光度数分别为0.05±0.01,37.02±5.38,1.08±0.67D,均显著小于术后(分别为0.45±0.13,46.27±7.02,1.92±0.73D),差异均具有统计学意义(P<0.05);术前角膜厚度为492.33±18.27μm,显著大于术后377.27±22.49μm(P<0.05);本组手术前后视力差异具有统计学意义(P<0.05);术后随访6mo,未见原有角膜病变复发,仅2例术后出现轻微角膜上皮下雾状混浊,给予激素类滴眼液点眼后均完全消退。结论:准分子激光术在治疗大泡性角膜病变中的临床疗效非常显著,安全性高,应在临床上进行推广。 To investigate the clinical efficacy and safety of phototherapeutic keratectomy ( PTK ) in the treatment of bullous keratopathy ( BK) .METHODS: A retrospective analysis of 60 cases ( 60 eyes) of BK patients from Department of Ophthalmology in our hospital October 2011 to July 2014 was undergone. Clinical data of all patients with treatment of PTK were analyzed. Best corrected visual acuity ( BCVA ) , corneal curvature, corneal astigmatism, corneal thickness and corneal endothelial cell density ( ECD ) , postoperative complications before and after surgery were compared. RESULTS: BCVA, corneal curvature, corneal astigmatism of patients before surgery were 0. 05 ± 0. 01 and 37. 02±5. 38, 1. 08±0. 67D, which were significantly less than those of postoperative ( respectively 0. 45 ± 0. 13 and 46. 27 ± 7. 02, 1. 92 ± 0. 73D ), the differences were statistically significant (all P〈0. 05). Corneal thickness of patients was 492. 33 ± 18. 27μm before surgery, which was higher than that after surgery 377.27±22.49μm (P〈0.05). The difference of visual acuity before and after surgery was statistically significant in this group (P〈0. 05). During the follow-up period of 6mo, no recurrence of the original corneal lesions, only 2 cases of postoperative slight haze, it was completely dissipated after given the hormone eye drops. CONCLUSlON: Excimer laser technology has high safety in the treatment of bullous keratopathy, it should be promoted in clinical practice.
出处 《国际眼科杂志》 CAS 2015年第2期326-328,共3页 International Eye Science
关键词 准分子激光术 大泡性角膜病变 临床疗效 安全性 excimer laser technology bullous keratopathy clinical efficacy safety
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