摘要
目的观察氯吡格雷联合氟伐他汀治疗脑梗死的临床效果。方法选取本院2013年1月~2014年6月收入院的脑梗死患者61例,采取随机数字表法分为对照组（31例）和治疗组（30例）,对照组给予抗血小板、降血压、胰岛素控制血糖等常规治疗;治疗组在常规治疗的基础上加用氯吡格雷75 mg,1次/d口服,氟伐他汀40 mg,晚睡前口服。1周为1个疗程,治疗两个疗程。治疗后,比较治疗前后两组患者的C-反应蛋白、血脂变化情况及临床疗效。结果治疗后,治疗组的C-反应蛋白、TC及LDL-C水平均低于对照组,差异有统计学意义（P〈0.05）;治疗组总有效率为93.33%,高于对照组的83.87%,差异有统计学意义（P〈0.05）。结论氯吡格雷联合氟伐他汀治疗脑梗死能明显改善患者病情,效果显著,值得临床推广应用。
Objective To observe the clinical efficacy of clopidogrel combined with fluvastatin in treatment of cerebral infarction. Methods 61 cases of patients with cerebral infarction treated in our hospital from January 2013 to June2014 were selected,and were randomly divided into control group（31 cases） and treatment group（30 cases）.The control group were taken with antiplatelet,lowering blood pressure,insulin to control blood sugar and other conventional treatment,on the basis of conventional treatment,the treatment group were taken with clopidogrel 75 mg oral,once a day;fluvastatin 40 mg,before sleep,oral.One week as a course,two courses of treatment. C-reactive protein,blood lipid changes and clinical efficacy of the two groups was compared. Results After treatment,C-reactive protein,TC and LDL-C of treatment group was lower than that of control group,the difference was significant（P〈0.05）.The total effective rate of treatment group was 93.33%,higher than 83.87% of the control group,the difference was significant（P〈0.05）. Conclusion Clopidogrel combined with fluvastatin in treatment of cerebral infarction can significantly improve the patients′condition,the efficacy is significant,and is worthy of clinical promotion.
出处
《中国当代医药》
2015年第4期85-87,共3页
China Modern Medicine
关键词
脑梗死
氯吡格雷
氟伐他汀
Cerebral infarction
Clopidogrel
Fluvastatin
