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甲状腺自身抗体阳性孕妇妊娠并发症发生情况分析 被引量：11

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摘要 目的分析妊娠期甲状腺自身抗体阳性与主要妊娠并发症发生情况的关系,探讨甲状腺球蛋白抗体(Tg Ab)是否作为妊娠期甲状腺疾病的筛查指标。方法检测妊娠晚期孕妇的甲状腺过氧化物酶抗体(TPOAb)及Tg Ab,根据检测结果分为TPOAb及Tg Ab均阳性组、单纯TPOAb阳性组、单纯Tg Ab阳性组,把TPOAb及Tg Ab均阴性者作为对照组,分析各组间主要妊娠并发症的发生情况。结果 TPOAb阳性检出率9.72%,Tg Ab阳性检出率10.76%,双抗体阳性检出率6.13%;TPOAb及Tg Ab均阳性组妊娠期高血压疾病、早产及胎膜早破的发生率均高于对照组,单纯Tg Ab阳性组胎膜早破的发生率也高于对照组,差异均有统计学意义(均0.05)。结论把Tg Ab作为妊娠期甲状腺疾病的筛查指标;在妊娠早期孕妇中开展TPOAb及Tg Ab的筛查,对抗体阳性者进行预防,减少妊娠并发症的发生。
作者 舒立波 屈煜 杨秀萍
机构地区 宁波市妇女儿童医院
出处 《现代实用医学》 2015年第1期83-85,共3页 Modern Practical Medicine
基金 浙江省医药卫生科技计划项目(2013KYB240) 中国疾病预防控制中心妇幼保健中心"西部地区妇幼卫生能力提升项目"(2014FYQ-3)
关键词 妊娠 高血压疾病 甲状腺过氧化物酶抗体 甲状腺球蛋白抗体 早产 胎膜早破
分类号 R714.25 [医药卫生—妇产科学]
  • 相关文献

参考文献9

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二级参考文献138

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二级引证文献84

现代实用医学
2015年 第1期

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