超声引导下C_5与颈浅丛联合阻滞在锁骨手术中局麻药的半数有效剂量被引量：9

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摘要目的测定超声引导下C5与颈浅丛联合阻滞在锁骨手术中局麻药的半数有效剂量。方法择期拟行锁骨骨折切开复位钢板螺钉内固定术患者40例,性别不限,年龄18~65岁,ASA分级Ⅰ~Ⅱ级,采用超声引导下C5和颈浅丛联合阻滞,即先在C5臂丛神经的周围注射1/2局麻药,穿刺针越过C5臂丛神经在胸锁乳突肌下缘再次注射余下1/2局麻药。局麻药为0.375%左布比卡因和1%利多卡因的混合液。局麻药的剂量分别由低到高设为8、12、16、20和24 m L,初始剂量16 m L,间隔剂量为4 m L,注药30 min后切皮时,若视觉模拟评分（VAS）〉3分,改为全身麻醉以及下一例采用高一级剂量。若VAS≤3分,则下一例采用低一级剂量。采用Probit法计算超声引导下C5与颈浅丛联合阻滞在锁骨手术中局麻药的半数有效剂量及其95%可信区间（CI）。结果超声引导下C5与颈浅丛联合阻滞在锁骨手术中局麻药的半数有效剂量为15.6 m L,95%CI为12.8~18.4 m L。结论超声引导下C5与颈浅丛联合阻滞在锁骨手术中局麻药的半数有效剂量为15.6 m L。

作者傅志海吴雅松陈再治吴雪梅王琛

机构地区福建省厦门市第三医院麻醉科苏州大学附属第二医院麻醉科

出处《广东医学》 CAS 北大核心 2015年第2期285-287,共3页 Guangdong Medical Journal

基金福建省卫生厅青年科研课题(编号:2012-291)

关键词锁骨超声检查臂丛颈丛神经传导阻滞

分类号 R978.5 [医药卫生—药品]

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