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p27^(kip1)蛋白在心血管疾病中的作用研究进展 被引量:2

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摘要 p27蛋白广泛抑制各种Cyclin和细胞周期蛋白依赖激酶(CDK)的活性,具有参与细胞周期调控、诱导凋亡、促进细胞分化等多种生物学功能。心血管疾病中大多以细胞增殖为基础,尤其是心室肥厚为其形态学表现。研究发现p27与这些疾病的发生、发展密切相关。因此,进一步研究阐明p27蛋白的作用机制,有望找到治疗某些心血管疾病的新靶点。
出处 《西南军医》 2015年第1期83-85,共3页 Journal of Military Surgeon in Southwest China
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