摘要
目的分析医院抗菌药物不良反应(ADR)相关因素,促进合理用药。方法对医院2013年收集上报的81例抗菌药物ADR进行回顾性统计分析。结果 ADR 81例,喹诺酮类引起ADR最多(46.91%),给药途径以静脉滴注引起ADR最常见(91.36%),临床表现以皮肤及其附件损害居多(69.14%)。结论抗菌药物ADR发生主要与患者年龄、给药途径、给药频次相关。应重视抗菌药物ADR报告与监测工作,保障用药安全。
Objective To analyze related factors by antibacterial drug with adverse reaction (ADR) in our hospital in order to promote the rational use of drugs. Methods 81 cases of antimicrobial drug ADR reports was to be retrospective sta- tistical analysis in our hospital in 2013. Results 81 cases of ADR showed clearly that 4-Quinolones caused the most of ADR ( accounted for 46.91% ). In the drug delivery way, the intravenous drip caused ADR was the most common ( accounted for 91.36% ) , and the clinical manifestation was to see more lesions of skin and its accessories( accounted for 69.14% ). Conclu- sion The ARD of antibacterial drug occurred mainly in relation to patients' age, administration route and dosing frequency. We should pay more attention to ADR report and supervision for ensuring the safety of drug use.
出处
《临床合理用药杂志》
2015年第5期8-9,共2页
Chinese Journal of Clinical Rational Drug Use
关键词
抗菌药物
药品不良反应
监测
分析
合理用药
Antibacterial drugs
Adverse drug reactions
Monitoring
Analysis
Rational drug use