摘要
目的 探讨新生儿重症监护病房医院感染的高危因素。方法 分析2013年5月~2014年8月滨州医学院烟台附属医院新生儿重症监护室收治的1650例患儿的临床资料。根据是否发生医院感染进行临床分组,医院感染组150例和非感染组1500例。观察两组小于胎龄儿、出生体重≤1500 g、胎龄≤37周、羊水污染、新生儿窒息、肠外营养、机械通气情况。采用多因素Logistic回归分析新生儿重症监护病房医院感染的高危因素。结果 两组新生儿出生体重≤1500 g、胎龄≤37周、新生儿窒息、肠外营养、机械通气差异均有统计学意义（均P〈0.05）;多因素Logistic回归分析,出生体重≤1500 g、胎龄≤37周、新生儿窒息、肠外营养、机械通气均是新生儿重症监护病房医院感染高危因素（OR=1.818、4.468、4.049、4.897、3.768,P〈0.05）。结论 及时规避新生儿重症监护病房医院感染高危因素,对于预防新生儿重症监护病房医院感染具有重要的意义。
Objective To approach high risk factors of hospital infection in Neonatal Intensive Care Unit （NICU）. Methods Clinical data of 1650 cases of newborn from May 2013 to August 2014 in NICU of Yantai Affiliated Hospital of Binzhou Medical University were analyzed. According to whether the hospital infection in clinical, they were divided into two groups, hospital infection group 150 cases and non-hospital infection group 1500 cases. The small for gesta- tional age infant, birth weight ≤ 1500 g, gestational age ≤ 37 weeks, amniotic fluid contamination, asphyxia neonatorttm, parcnteral alimentation, mechanical ventilation of two groups were detected, the high risk factors of hospital infection in NICU were analyzed by Logistic regression analysis. Results The differences of birth weight ≤ 1500 g, gestational age ≤37 weeks, asphyxia neonatorum, parenteral alimentation, mechanical ventilation between two groups were statistical sig- nificance （all P 〈 0.05）, the Logistic regression analysis showed that, birth weight≤1500 g, gestational age≤ 37 weeks, asphyxia neonatorum, parenteral alimentation, mechanical ventilation were high risk factors of hospital infection in NICU （OR=1.818, 4.468, 4.049, 4.897, 3.768, all P 〈 0.05）. Conclusion Avoiding high risk factors of hospital infection in NICU timely is an important meaning for prevention of hospital infection in NICU.
出处
《中国医药导报》
CAS
2015年第5期48-51,共4页
China Medical Herald
