摘要
目的:探讨抗甲状腺药物对妊娠合并甲状腺功能亢进患者的治疗效果及对胎儿的影响。方法:选取2009年5月—2014年5月收治的妊娠合并甲状腺功能亢进患者96例,随机分成对照组和观察组,每组48例。对照组患者不接受抗甲状腺药物治疗,观察组接受抗甲状腺药物治疗。对两组患者甲状腺功能、孕妇并发症以及新生儿平均体重和1 min Apgar评分进行分析比较。结果:观察组患者的游离三碘甲状腺原氨酸(FT3)、游离甲状腺激素(FT4)以及血清促甲状腺激素(TSH)水平均显著低于对照组;观察组并发症发生率显著低于对照组,差异均有统计学意义(P<0.05)。结论:抗甲状腺药物可以显著改善妊娠合并甲状腺功能亢进患者的甲状腺功能,并可增加胎儿体重,提高Apgar评分。
Objective： To investigate the efficacy of antithyroid drugs on pregnant women with hyperthyroidism and the impact on fetus. Methods： 96 cases of pregnant women with hyperthyroidism in our hospital from May 2009 to May 2014 were selected and randomly divided into control group and observation group,each group 48 cases. Patients in control group were not administrated with anti- thyroid drugs,and patients in observation group were dealed with antithyroid drugs. The thyroid function,the pregnant women complications,the newborn average weight and the one minute Apgar scores of two groups were analyzed and compared. Results： The FT3,FT4 and TSH levels of observation group were significantly lower than control group（ P〈 0. 05）. The pregnant women complications rate of observation group was significantly lower than control group（ P 0. 05）.The newborn average weight of observation group was significantly higher than control group,and the Apgar score high of observation group was significantly higher than control group. The differences were statistically significant（ P 〈0. 05）. Conclusion：For pregnant women with hyperthyroidism,antithyroid drugs can significantly improve thyroid function,the newborn average weight and one minute Apgar scores.
出处
《临床医药实践》
2015年第2期98-100,共3页
Proceeding of Clinical Medicine
