摘要
随着分子生物学的发展,人们对慢性功能性便秘发病机制的研究大多从肠神经系统(ENS)、神经递质、结肠Cajal细胞(ICC)、水通道蛋白、胃肠激素和自由基分泌等方面进行,因此动物模型是实验研究慢性功能性便秘的一个重要环节。该文从建立便秘动物模型和复方中药研究发病机理两方面进行综述,并在此基础上提出目前研究尚存的问题和今后深入研究的方向。
With the development of the molecular biology people research the pathogenesis of chronic functional constipation from different aspects,including enteric nervous system（ENS）,neurotransmitter,interstitial cells of Cajal（ICC）,aquaporins,gastrointestinal hormone and free radical. So constipation animal model is very necessary in the experimental research of chronic functional constipation. This article sums up the animal model establishment of constipation and research of the pathogenesis and then points out the problems and the developmental trend in future.
出处
《辽宁中医药大学学报》
CAS
2015年第3期219-222,共4页
Journal of Liaoning University of Traditional Chinese Medicine
关键词
便秘
实验研究
综述
constipation
experimental research
review
