摘要
目的通过对甲状腺结节患者能谱曲线及能谱特征参数分析,探讨宝石CT能谱成像(GSI)技术对甲状腺良恶性结节的鉴别诊断价值。资料与方法对经病理证实的39例甲状腺结节患者行GSI三期增强扫描,分析碘/水物质含量、有效原子序数及表化后的碘浓度比(病灶碘浓度与同期相颈动脉碘浓度的比值),计算能谱曲线斜率。结果 GSI三期增强扫描中,良性结节的碘浓度均明显高于恶性结节,差异有统计学意义(P<0.05);两组间碘浓度比在动脉期和静脉期差异有统计学意义(P<0.01);在平扫期和动脉期,良性结节的能谱曲线斜率明显大于恶性结节,差异均有统计学意义(P<0.05);两组间水浓度、有效原子序数在各期相差异均无统计学意义(P>0.05)。结论甲状腺良恶性结节具有不同的平扫+增强GSI特征,应用GSI的多种参数对术前鉴别甲状腺结节良恶性具有很大的潜能。
Purpose To discuss the value of gemstone spectral imaging （GSI） in distinguishing malignant thyroid nodules from benign ones through the analysis of parameters like spectral curve and spectral features in patients with thyroid nodules. Materials and Methods Thirty-nine patients with thyroid nodules confirmed pathologically underwent triple-phase enhanced GSI. The features such as iodine concentration, water concentration, effective atomic number and normalized iodine concentration （NIC, obtained by dividing the iodine concentration of tumor to that of carotid artery） were analyzed and the slope of spectral curve of the nodules at each phase was calculated. Results On the triple-phase enhanced GSI, the Iodine concentration of benign thyroid nodule was significantly higher than that of malignant thyroid nodules （P〈0.05）; the N1C at arterial phase and venous phase showed significant difference between the two groups （P〈0.01）; the slope of spectral curve of benign nodules was significantly larger than that of malignant nodules on plain scan and at arterial phase respectively （P〈0.05）; however, the water concentration and effective atomic number had no difference at each phase between the two groups （P〉0.05）. Conclusion Benign and malignant thyroid nodules show different features on plain and enhanced GSI, which means that various parameters of GSl could be used in the differentiation of thyroid nodules before operation.
出处
《中国医学影像学杂志》
CSCD
北大核心
2014年第12期908-911,共4页
Chinese Journal of Medical Imaging
关键词
甲状腺结节
甲状腺肿瘤
体层摄影术
X线计算机
宝石能谱成像
诊断
鉴别
Thyroid nodule
Thyroid neoplasms
Tomography, X-ray computed
Gemstone spectral imaging
Diagnosis, differential
