摘要
癫痫是一种慢性反复发作性疾病，经正规治疗仍有20%～30%患者对抗癫痫药物耐药而发展成为难治性癫痫，进而求助于手术、生物疗法，但这些方法价格昂贵、疗效不确定。明确癫痫的耐药机制，发展新型的神经治疗措施是大势所趋。现就癫痫的耐药机制作一综述。
Epilepsy is a chronic, recurrent paroxysmal disease. About 20%-30% of epilepsy patients are resistant to anti-epilepsy drugs after rational therapy. Finding another way to treat this disease, such as surgery and physiotherapy is expensive and the efficacy is unknown. It’s necessary to develop new neurological strategies according to the mechanism of drug-resistance in epilepsy, which was reviewed in this paper.
出处
《中华临床医师杂志（电子版）》
CAS
2015年第4期115-119,共5页
Chinese Journal of Clinicians(Electronic Edition)
基金
国家自然科学基金项目(81373586)
北京中医药大学科研创新团队项目(2011-CXTD-23)
关键词
癫痫
耐药
Epilepsy
Drug-resistance
