摘要
目的:总结分析长脉宽1 064 nm掺钕钇铝石榴石(Nd∶YAG)激光、595 nm脉冲染料激光(PDL)或两者联合治疗会阴部婴幼儿血管瘤临床疗效、不良反应及其影响疗效的有关因素。方法:应用长脉宽1 064 nm Nd∶YAG激光、脉冲染料激光或两者联合治疗会阴部婴幼儿血管瘤35例,治疗间隔4~8周。统计治疗效果并分析影响疗效的因素。结果:35例患儿,其中男3例、女32例,年龄40 d^2岁,皮损面积0.1~15 cm2。治疗有效率为100%,治疗次数1~5次。常见的不良反应为红肿和水疱,一般3~5 d内修复,其中2例出现糜烂及渗出,5例痊愈后皮肤质地有变化,2例遗留色素沉着,未见感染、瘢痕等其他不良反应。结论:长脉宽1 064 nm Nd∶YAG激光及595 nm脉冲染料激光治疗会阴部婴幼儿血管瘤安全有效,不良反应轻微,值得推广应用。
Objectives： To analyze the clinical efficacy, adverse reaction and the factors related to the efficacy for the treat- ment of perineal infantile hemangioma by long-pulsed 1 064 nm Nd：YAG laser or 595 nm pulsed dye laser or combination of the two lasers. Methods： Thirty-five cases of perineal infantile hemangioma were treated with long-pulsed 1 064 nm Nd：YAG laser or 595 um pulsed dye laser or the combination of the two lasers. The course of treatment was 4-8 weeks. Statistical analysis of the efficacy and the factors influencing therapeutic effects were carried out. Results： Thirty-five cases, including 3 male and 32 female, aged 40 days to 2 years, and the areas of lesions ranged from 0.1-15 cm^2. The total effective rate was 100% after 1-5 times of treatment. The common adverse reactions were erythema, edema and blister, which healed within 3-5 days, The skin texture of 5 cases was changed after being cured, 2 cases had hypcrpigmentation, and infection, scar formation and other adverse reactions were not observed. Conclusions： Long-pulsed 1 064 nm Nd：YAG laser or 595 nm pulsed dye laser are safe and effective for the treatment of perineal iniantile hemangioma with mild adverse reactions, which can be widely used.
出处
《临床皮肤科杂志》
CAS
CSCD
北大核心
2015年第2期116-119,共4页
Journal of Clinical Dermatology
