期刊文献+

新疆哈萨克族与汉族老年急性脑梗死患者脑卒中后抑郁对比分析 被引量:8

Post-stroke depression in elderly Kazak and Han ethnic patients with acute cerebral infarction in XinJiang: a comparison study
原文传递
导出
摘要 目的 探讨新疆哈萨克族与汉族老年急性脑梗死患者脑卒中后抑郁(PSD)的抑郁、焦虑严重程度及临床表现有无差异。 方法 以新疆奎屯第七师医院神经内科、新疆伊利哈萨克自治州奎屯医院神经内科及乌鲁木齐市友谊医院神经内科自2011年7月至2014年7月收治的发病7d内入院的447例哈萨克族及汉族老年急性脑梗死患者为研究对象,根据PSD的临床诊断标准及汉密尔顿抑郁量表(HAMD)评分,确定哈萨克族PSD组患者40例及汉族PSD组患者78例,对比分析2组患者HAMD量表总分、汉密尔顿焦虑量表(HAMA)总分及各因子评分以及临床特点。 结果 汉族HAMD量表总分较哈萨克族增高,汉族阻滞、睡眠障碍、绝望感因子分值较哈萨克族增高,差异有统计学意义(P<0.05);哈萨克族HAMA量表总分较汉族增高,哈萨克族精神性焦虑因子分值较汉族增高,差异有统计学意义(P<0.05)。哈萨克族发生烦燥不安、紧张激越、心血管症状人数较汉族增多,差异有统计学意义(P<0.05);汉族在失眠、早醒、对身体过分关注、疑病、对未来悲观、绝望、胃肠道症状人数较哈萨克族增多,差异有统计学意义(P<0.05)。 结论 哈萨克族老年急性脑梗死PSD患者抑郁、焦虑严重程度及临床表现与汉族不同。 Objective To investigate the differences of severities of depression and anxiety,clinical manifestations in elderly Kazak and Han post-stroke depression (PSD) patients with acute cerebral infarction.Methods Four hundred and forty-seven elderly Kazak and Han Ethnic patients with acute cerebral infarction,admitted to our hospitals within 7 days of onset,were chosen; according to the clinical diagnostic criteria and Hamilton Depression Rating Scale (HAMD) scores for PSD,the patients were divided into Kazak PSD group (n=40) and Han PSD group (n=78).The scores of HAMD,Hamilton Anxiety Rating Scale (HAMA),and the clinical features were compared between the two groups.Results The HAMD scores in Han PSD group were significantly higher than those in Kazak PSD group:factor scores of block,sleep disorder,depression were statistically higher than those in Kazak PSD group (P〈0.05).The HAMA scores in Kazak PSD group were significantly higher than those in Han PSD group:the factor scores of mental anxiety were statistically higher than those in the Han PSD group (P〈0.05).The incidences of restlessness,nervous agitation,cardiovascular symptoms in Kazak PSD group were significantly higher than those in the Han PSD group (P〈0.05).The incidences of insomnia,waking up early,too much attention to the body,hypochondria,pessimism about future,gastrointestinal symptoms in Han PSD group were statistically higher than those in the Kazak PSD group (P〈0.05).Conclusion The severity of depression and anxiety,and clinical manifestations are various in elderly Kazak and Han PSD patients.
出处 《中华神经医学杂志》 CAS CSCD 北大核心 2015年第2期167-170,共4页 Chinese Journal of Neuromedicine
基金 新疆兵团第七师科技项目
关键词 急性脑梗死 脑卒中后抑郁 哈萨克族 汉族 Acute cerebral infarction Post-stroke depression Kazak ethnic Han ethnic
  • 相关文献

参考文献9

  • 1Taylor WD, Aizenstein ILl, Alexopoulos GS. The vascular depression hypothesis:mechanisms linking vascular disease with depression[J]. Mol Psychiatry, 2013, 18(9): 963 -974.
  • 2单培佳,周颖奇,毕晓莹,仇一青,王施.卒中后抑郁的危险因素和机制[J].国际脑血管病杂志,2012,20(12):939-942. 被引量:18
  • 3张君,陈春富,王维,李继川,郁飞宇.腔隙性脑梗死患者卒中后抑郁的临床分析[J].临床神经病学杂志,2012,25(6):449-451. 被引量:6
  • 4Nemeroff CB, Owens MJ. The role of serotonin in the pathophysiology of depression: as important as ever [J]. Clin Chem, 2009, 55(8): 1578-1579.
  • 5中国急性缺血性脑卒中诊治指南2010[J].中华神经科杂志,2010,43(2):146-153. 被引量:3406
  • 6中华医学会精神科分会.中国精神障碍分类及诊断标准[M].第3版.济南:山东科学技术出版社,2001:95-97.
  • 7Robinson RG, Spalletta G. Poststroke depression:a review[J]. Can J Psychinatry, 2010, 55(6): 341-349.
  • 8Boyko M, Kutz R, Gruenbaum BF, et al. The influence of aging on poststroke depression using a rat model via middle cerebral artery occlusion[J]. Cogn Affect Behav Neurosci, 2013, 13(4): 847-859.
  • 9Terroni L, Amarro E, Iosifescu DV, et al. Stroke lesion in cortical neural circuits and post-stroke incidence of major depressive episode: a 4-month prospective study[J]. World J Biol Psychiatry, 2011, 12(7): 539-548.

二级参考文献69

共引文献3429

同被引文献53

  • 1Dimitri Novitzky,David KC Cooper.Thyroid hormone and the stunned myocardium[J].The Journal of Endocrinology,2014,23(1):1-8.
  • 2Wilmar M Wiersinga.Paradigm shifts in thyroid hormone replacement therapies for hypothyroidism[J].Nature Re- views,2014,10(3);164-174.
  • 3Thomas J Stamm,Ute Lewitzka,Cathrin Sauer,et al.Sup- raphysiologic doses of levothyroxine as adjunctive thera- py in bipolar depression:A randomized,double-blind,placebo-controlled study[J].The Journal of Clinical Psy- chiatry,2014,75(2);162-168.
  • 4Michael Bauer,Tasha Glenn,Maximilian Pilhatsch,et al.Gender differences in thyroid system function;Relevance to bipolar disorder and its treatment[J].Bipolar Disorders,2014,16(1):58-71.
  • 5Dafu Yu,Heng Zhou,Yuan Yang,et al.The bidirectional effects of hypothyroidism and hyperthyroidism on anxiety- and depression-like behaviors in rats[J].Hormones and Behavior,2015,69(3):106-115.
  • 6Ewa Oglodek,Anna Szota,Aleksander Araszkiewicz.Elec- troconvulsive therapy in a patient with drug-resistant de- pression and thyroid hormone imbalance[J].The Australian and New Zealand Journal of Psychiatry,2014,48(1):96-97.
  • 7Jin-Fang Ge,Yun-Yun Peng,Cong-Cong Qi,et al.De- pression-like behavior in subclinical hypothyroidism rat induced by hemi-thyroid electrocauterization[J].Endocri- ne,2014,45(3):430-438.
  • 8Elie G Aoun5Mary R Lee,Carolina L Haass-Koffler,et al.Relationship between the thyroid axis and alcohol crav- ing[J].Alcohol and Alcoholism,2015,50(1):24-29.
  • 9Abdel Rahman EM,Mansour W,Holley JL.Thyroid hor- mone abnormalities and frailty in elderly patients with chronic kidney disease:A hypothesis[J].Seminars in Dial- ysis,2010,23(3):317-323.
  • 10Regis G Rosa,Alcina J S Barros,Antonio RB de Lima,et al.Mood disorder as a manifestation of primary hy- poparathyroidism:A case report[J].Journal of Medical Case Reports,2014,8(4):326.

引证文献8

二级引证文献56

相关作者

内容加载中请稍等...

相关机构

内容加载中请稍等...

相关主题

内容加载中请稍等...

浏览历史

内容加载中请稍等...
;
使用帮助 返回顶部