摘要
目的 探讨新疆哈萨克族与汉族老年急性脑梗死患者脑卒中后抑郁(PSD)的抑郁、焦虑严重程度及临床表现有无差异。 方法 以新疆奎屯第七师医院神经内科、新疆伊利哈萨克自治州奎屯医院神经内科及乌鲁木齐市友谊医院神经内科自2011年7月至2014年7月收治的发病7d内入院的447例哈萨克族及汉族老年急性脑梗死患者为研究对象,根据PSD的临床诊断标准及汉密尔顿抑郁量表(HAMD)评分,确定哈萨克族PSD组患者40例及汉族PSD组患者78例,对比分析2组患者HAMD量表总分、汉密尔顿焦虑量表(HAMA)总分及各因子评分以及临床特点。 结果 汉族HAMD量表总分较哈萨克族增高,汉族阻滞、睡眠障碍、绝望感因子分值较哈萨克族增高,差异有统计学意义(P<0.05);哈萨克族HAMA量表总分较汉族增高,哈萨克族精神性焦虑因子分值较汉族增高,差异有统计学意义(P<0.05)。哈萨克族发生烦燥不安、紧张激越、心血管症状人数较汉族增多,差异有统计学意义(P<0.05);汉族在失眠、早醒、对身体过分关注、疑病、对未来悲观、绝望、胃肠道症状人数较哈萨克族增多,差异有统计学意义(P<0.05)。 结论 哈萨克族老年急性脑梗死PSD患者抑郁、焦虑严重程度及临床表现与汉族不同。
Objective To investigate the differences of severities of depression and anxiety,clinical manifestations in elderly Kazak and Han post-stroke depression (PSD) patients with acute cerebral infarction.Methods Four hundred and forty-seven elderly Kazak and Han Ethnic patients with acute cerebral infarction,admitted to our hospitals within 7 days of onset,were chosen; according to the clinical diagnostic criteria and Hamilton Depression Rating Scale (HAMD) scores for PSD,the patients were divided into Kazak PSD group (n=40) and Han PSD group (n=78).The scores of HAMD,Hamilton Anxiety Rating Scale (HAMA),and the clinical features were compared between the two groups.Results The HAMD scores in Han PSD group were significantly higher than those in Kazak PSD group:factor scores of block,sleep disorder,depression were statistically higher than those in Kazak PSD group (P〈0.05).The HAMA scores in Kazak PSD group were significantly higher than those in Han PSD group:the factor scores of mental anxiety were statistically higher than those in the Han PSD group (P〈0.05).The incidences of restlessness,nervous agitation,cardiovascular symptoms in Kazak PSD group were significantly higher than those in the Han PSD group (P〈0.05).The incidences of insomnia,waking up early,too much attention to the body,hypochondria,pessimism about future,gastrointestinal symptoms in Han PSD group were statistically higher than those in the Kazak PSD group (P〈0.05).Conclusion The severity of depression and anxiety,and clinical manifestations are various in elderly Kazak and Han PSD patients.
出处
《中华神经医学杂志》
CAS
CSCD
北大核心
2015年第2期167-170,共4页
Chinese Journal of Neuromedicine
基金
新疆兵团第七师科技项目
关键词
急性脑梗死
脑卒中后抑郁
哈萨克族
汉族
Acute cerebral infarction
Post-stroke depression
Kazak ethnic
Han ethnic