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间充质干细胞的临床应用与问题研究 被引量:4

Clinical Applications of Mesenchymal Stem Cells and the Existent Problems
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摘要 近几年,间充质干细胞疗法作为一种治疗机体无法自然修复的组织细胞和器官损伤的多种难治性疾病的新方法取得了广泛关注。其有能力在体内和体外条件下分化成各种细胞系并进行大量扩增。间充质干细胞疗法在多个国家的基础试验中已证实了其安全性和有效性。随着研究的深入,人们逐渐发现间充质干细胞疗法的负面效应。该文对近年来关于间充质干细胞临床治疗效果调查情况及其在临床应用中存在的问题予以综述,以期为临床提供参考。 Currently,mesenchymal stem cell( MSC) therapy,as a new kind of therapeutic method,has achieved remarkable progress in treating multiple diseases with multiple tissue cell and organ injuries which are hard to recover naturally. They can differentiate into a variety of cell lines in vitro and in vivo,and have a strong capabilities of amplification. In many countries,MSC therapy has been confirmed safe and effective in the preclinical research. At the same time,people gradually found that the negative effects of MSC therapy. Here is to make a review of the effects of MSC therapy and discuss the existing problems of clinical application of MSC,in order to provide references to the clinical practice.
出处 《医学综述》 2015年第4期613-615,共3页 Medical Recapitulate
关键词 间充质干细胞 临床应用 干细胞治疗 Mesenchymal stem cells Clinical application Stem cell therapy
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