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复发性外阴阴道念珠菌感染及其耐药性分析 被引量:4

Analysis of recurrent vulvovaginal candidiasis and its resistance to antifungal agents
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摘要 外阴阴道念珠菌病是妇女最常见的外阴阴道炎症,致病菌多为白色假丝酵母菌。复发性念珠菌外阴阴道炎(RVVC)是指念珠菌外阴阴道炎经治疗临床症状和体征消失,真菌学检查连续3周期均为阴性后症状重现,真菌学检查又呈阳性,则属复发,RVVC的诊断比较困难,目前一般把1年中复发4次或以上的外阴阴道假丝酵母菌病(VVC)为RVVC〔1〕。以外阴阴道瘙痒,灼痛,白带增多为主诉,可伴尿痛及性交痛等症状. Recurrent vulvovaginal candidiasis(RVVC)is difficult to treat and easy to be recurrent in gynecologic diseases.Approximately 75% women have vulvovaginal candidiasis(VVC)at least once in their lifetime,among which there are 5%~10% patients develop to RVVC.The predominant pathogen in RVVC is Candida albicans,non-C.albicans infection is upgraded manifestly.RVVC is easy to be developed by the long-term irregular use of antifungal,long-term use of broad-spectrum antibiotic,endogenous reinfection,iterative vaginal irrigation and so on.Recent studies suggest that the candida isolates obtained from patients were susceptible to nystatin and amphotericin B,but were less so to Pyrroles.So the therapy must be decided according to the fungus culture and susceptibility test results.
作者 杨成良 谭超
出处 《临床血液学杂志(输血与检验)》 CAS 2015年第1期179-181,共3页 Journal of Clinical Hematology(Blood Transfusion & Laboratory Medicine)
基金 宜昌市科技研究与开发项目(No:A12301-25)
关键词 复发性外阴阴道念珠菌病 假丝酵母菌 耐药 recurrent vulvovaginal candidiasis candida resistance
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