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抗生素相关性腹泻临床探讨 被引量:8

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摘要 目的:探究抗生素相关性腹泻的临床表现及预防方法。方法:对2011年6月-2014年6月笔者所在医院120例抗生素相关性腹泻患者的临床资料进行回顾性分析,统计抗生素相关性腹泻的发生率;分析与抗生素的使用关系,探究其影响因素。结果:抗生素相关性腹泻的发生率为6.28%;粪便性状主要为稀水泡沫样便,占70.00%,伴有黏膜脱落坏死及黏液(含脓血)各占5.00%、25.00%。观察组患者的平均年龄明显大于对照组,抗菌应用时间明显长于对照组,使用的抗菌药物种类明显多于对照组,差异均有统计学意义(P<0.05);观察组采用干预措施(鼻饲、器官插管、器官切开、泌尿道插管等)患者62例,对照组患者192例,比较差异有统计学意义(P<0.05);两组患者应用预防抗菌药物、给药途径比较差异均无统计学医院(P>0.05)。结论:抗生素相关性腹泻的发生率较高,与多种影响因素有关,应合理选择抗菌药物;减少侵入性操作;避免预防应用抗菌药物,尽量减少联合用药;应用抗菌药物的患者可适当补充益生菌。
作者 杨红 石建丽
出处 《中外医学研究》 2015年第6期123-125,共3页 CHINESE AND FOREIGN MEDICAL RESEARCH
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