期刊文献+

从ASCO 2013年度报告看肺癌临床进展

下载PDF
导出
摘要 肺癌是全球发病率和病死率最高的恶性肿瘤,严重影响着人类健康。肺癌患者生存期的明显改善,源于对肺癌驱动基因研究成果的应用和相关靶向治疗药物的开发及使用。2013年的美国临床肿瘤学会(ASCO)防癌年度报告显示,肺癌防癌筛查、肿瘤靶基因检测及相关靶向治疗等方面的研究均获得了一定的成果,本文予以解读。
作者 陈惠 张力
出处 《癌症进展》 2014年第6期541-544,共4页 Oncology Progress
关键词 肺癌 ASCO
  • 相关文献

参考文献11

  • 1Church TR, Black WC, Aberle DR, et al. Results of ini- tial low-dose computed tomographic screening for lung cancer[J]. N Engl J Med, 2013, 368: 1980-1991.
  • 2Bach PB, Mirkin JN, Oliver TK, et al. Benefits and harms of CT screening for lung cancer: A systemic re- view[J]. JAMA, 2012, 307: 2418-2429.
  • 3Johnson BE, Kris MG, Berry LD, et al. A multicenter ef- fort to identify driver mutations and employ targeted therapy in patients with lung adenocarcinomas: the Lung Cancer Mutation Consortium (LCMC)[J]. J Clin Oncol, 2013, 31(15 Suppl): Abstr 8019.
  • 4Barlesi F, Blons H, Beau-Faller M, et al. Biomarkers (BM) France: results of routine EGFR, HER2, KRAS, BRAF, PI3KCA mutations detection and EML4-ALK gene fusion assessment on the first 10,000 non-small cell lung cancer (NSCLC) patients (pts)[J]. J Clin On- col, 2013, 31(15 Suppl): Abstr 8019.
  • 5Varella-Garcia M, Xu LG, Mahale S, et al. RET rear- rangements detected by FISH in "pan-negative" lung adenocareinoma[J]. J Clin Oncol, 2013, 31(15 Suppl): Abstr 8024.
  • 6Dela Cruz Drilon AE, Wang L, Hasanovic A, et al. Screening for RET and ROS1 fusions in an enriched co- hort of pan-negative never-smokers with advanced lung adenocarcinomas to identify patients for treatment in tar- geted therapy trials[J]. J Clin Oncol, 2013, 31(15 Sup- pl): Abstr 8067.
  • 7Planchard D, Mazieres J, Riely GI, et al. Interim results of phase II study 13RFl13928 of dabrafenib in BRAF V600E mutation - positive non-small cell lung cancer (NSCLC) patients[J]. J Clin Oncol, 2013, 31(15 Suppl): Abstr 8009.
  • 8Shaw AT, Ou SH, Bang YJ, et al. Efficacy and safety of crizotinib in patients with advanced ROS1-rearrangednon-small cell lung cancer (NSCLC) [J]. J Clin Oncol, 2013, 31(15 Suppl): Abstr 8032.
  • 9US Food and Drug Administration: Approved drugs: Pa- clitaxel (Abraxane). http://www.fda.gov/drugs/ informa- tionondrugs/approveddrugs/ucm323668.htm.
  • 10US Food and Drug Administration: Approved drugs: Er-lotinib, http://www, fda.gov/drugs/informationondrugs/ap- proveddrugs/ucm352317.htm.

相关作者

内容加载中请稍等...

相关机构

内容加载中请稍等...

相关主题

内容加载中请稍等...

浏览历史

内容加载中请稍等...
;
使用帮助 返回顶部