摘要
目的研究关爱家园HIV/AIDS患者合并其他病原体感染情况分析及多重感染对HIV/AIDS的影响,为HIV/AIDS防控和综合治疗提供科学依据。方法采用ELSIA法检测丙肝抗体(抗-HCV)、EB病毒抗体(EBAb)、科萨奇病毒抗体(CoxAb);TORCH采用胶体金法进行检测;用流式细胞仪检测HIV感染者全血中的CD4/CD8细胞,检测结果分组,组间采用卡方检验。结果 321例HIV阳性患者单纯合并乙肝病毒(HBV)感染37例(11.53%);单纯合并丙肝病毒(HCV)感染8例(2.49%);单纯合并梅毒螺旋体(TP)感染107例(33.33%);单纯合并巨细胞病毒(CMV)感染4例(1.25%)。结论 HIV阳性患者容易合并多种病原体感染,尤其以梅毒螺旋体感染常见。
Objective To analyze the impacts of the co-infection with other pathogens in HIV/AIDS patients,so as to provide scientific basis for prevention,control and comprehensive treatment of HIV/AIDS.Methods The antibodies of HCV,EB and Cox were detected by enzyme-linked immunosorbent assay（ELISA）.Toxoplasmosis,other（viruses）,rubella cytomegalovirus（CMV）,herpes（TORCH） were detected using colloidal gold method.The CD4/CD8 cells in the whole blood of the patients were determined by flow cytometry.Then the patients were grouped according to the detection results to compare the data by chi-square test.Results Among 321 HIV-positive patients,co-infection of HIV and HBsAg was found in 37 cases（11.53%）,co-infection of HIV and HCV was found in 8 cases（2.49%）,co-infection of HIV and TPPA was found in 107cases（33.33%）,and co-infection of HIV and CMV was found in 4 cases（1.25%）.Conclusion Multiple pathogens co-infection was common in HIV-positive patients,especially co-infection with Treponema pallidum.
出处
《中国卫生检验杂志》
北大核心
2014年第13期1955-1957,共3页
Chinese Journal of Health Laboratory Technology
