摘要
目的:观察康复新液联合三联疗法对胃溃疡患者临床疗效以及胃黏膜PGE2(前列腺E2)、血清MMP-9(基质金属蛋白酶-9)含量的影响。方法:将82例胃溃疡患者随机分为两组,对照组采用三联疗法治疗;观察组采用三联疗法加康复新液治疗,观察两组临床疗效、Hp根除率、复发率及治疗前后胃黏膜PGE2和血清MMP-9含量的变化。结果:观察组的临床疗效明显优于对照组,两组均可升高胃黏膜PGE2含量,降低血清MMP-9含量,观察组作用优于对照组。结论:康复新液联合三联疗法是治疗胃溃疡的有效方法,可能与其影响胃黏膜PGE2、血清MMP-9含量有关。
Objective： To observe the effects of Kangfuxin liquid combined with triple therapy on gastric ulcer and the influence on gastric mucosal PGE2 and serum matrix metalloproteinase- 9 levels. Methods： 82 cases with gastric ulcer were randomly divided into two groups,patients in control group received triple therapy,patients in treatment group accepted Kangfuxin liquid combined with triple therapy. The clinical efficacy,HP eradication rate,gastric mucosal PGE2,serum serum matrix metalloproteinase- 9 and recurrence rate in both groups were observed. Results： The curative effect of Kangfuxin group was obvious better than that of control group,the gastric mucosal PGE2 content was increased and serum MMP- 9 level was decreased. the effects of Kangfuxin group were better than those of control group. Conclusion： Kangfuxin liquid combined with triple therapy was an effective method in treatment of gastric ulcer,its mechanism maybe related to the influence on gastric mucosal PGE2 content and serum matrix metalloproteinase- 9 level.
出处
《中国中医药科技》
CAS
2015年第1期19-20,共2页
Chinese Journal of Traditional Medical Science and Technology
基金
浙江省湖州市科技计划项目(2012C33213)
