摘要
目的：探讨颅内孤立性纤维瘤（I-SFT）的MRI表现。方法：回顾性分析8例经手术病理证实的I-SFT的MRI及病理学资料。结果：肿瘤发生在幕下2例,幕上3例（其中侧脑室内1例）,跨越幕上及幕下2例,鞍区1例。1例鞍区肿瘤在T1WI、T2WI上呈均匀等信号,其余7例信号不均,T1WI、T2WI上以等、稍高信号为主,其中5例T2WI见小斑片状低信号区,3例见囊变灶,5例病灶内可见粗大流空血管影。MRI增强扫描示8例均明显强化;鞍区肿瘤强化均匀,其余7例强化不均;5例T2WI低信号区明显强化,3例囊变区未见强化,2例可见脑膜尾征。除侧脑室内1例周围脑实质水肿明显外,其余7例无或轻度水肿。病理显示8例均见丰富的小梭形细胞;免疫组化显示CD34（-）,CD99（＋）,Bcl（＋）,Vimentin（＋）,EMA（-）。结论：I-SFT的MRI表现有一定的特点,当脑膜肿瘤呈等、较高信号,增强呈明显强化,其内出现粗大流空血管、T2WI低信号区时,可考虑该病诊断,但其确诊仍需依靠组织病理学。
Objective ： To investigate the MRI features of intracranial solitary fibrous tumors （I-SFT）. Methods：MRI findings in 8 cases of pathologically proved I-SFT were retrospectively analyzed,and compared with pathologic histology. Results;One lesion arose from the lateral ventricle, the other 7 lesions were derived from the dura mater. The lesions were located in infratentorial （n; 2）, supratentorial （n ; 3）, across supratentorial and infratentorial （n ; 2） and sella area （n 1）. On pre-contrast MRI,the lesion in the sella area showed isointense signal on T1 WI and T2 WI, other 7 lesions showed isointense or slightly hyperintense signals mainly on T1 WI and T2WI including cystic portion in 3 lesions,hypointense signals in 5 lesions on T2WI and flow void vascular signals in 5 lesions. All lesions were enhanced obviously, sellar lesion showed homogeneous enhancement,and others heterogeneous enhancement. There was intensive enhancement in low signal area on T2WI in 5 cases,cystic portion was not enhanced. Dural tail was found in 2 lesions. The only lesion in the lateral ventricle showed obvious edema of surrounding tissue, while the other 7 cases had slight or no edema. The pathology showed that there were rich small spindle cells in all the 8 cases. Immunohistochemical examination showed CD34 （ - ）, CD99 （＋ ）, Bcl （ ＋ ）, Vimentin （ ＋ ）, EMA （ - ）. Conclusion ; MRI manifestation of I-SFT has its own features, if the meningeal tumors show isointense or slightly hyperintense signals, with coarse vascular signal void and intensive enhancement of the area with low T2 signal, diagnosis of solitary fibrous tumor could be considered. But its confirmation still depends on histopathology.
出处
《放射学实践》
北大核心
2015年第2期127-130,共4页
Radiologic Practice
关键词
孤立性纤维瘤
磁共振成像
病理学
Solitary fibrous tumor
Magnetic resonance imaging
Pathology
