摘要
目的总结近年来我院食管癌患者行三维适形及调强适形放疗时对心脏放射性损伤的监测、观察其影响。方法对2011年8月-2014年2月在我院行食管癌放射治疗的102例患者,分为普通放疗组和适形放疗组,在放疗前后及放射治疗后3个月内分别检查患者心电图、心肌酶谱、心肌肌钙蛋白、超声心动图和胸部CT等,进行统计学分析。结果普通放疗组患者49例出现急性放射性损伤39例,占79.6%,适形放疗组患者53例出现急性放射性心脏损伤32例,占60.4%,χ^2=3.938,P〈0.05,差异有统计学意义。结论食管癌患者适形放疗对累及心脏照射剂量及体积予以适当限制,可以减轻急性放射性心脏损伤。
Objective To observe the influences of radiation-induced heart damage after three-dimensional conformal radiotherapy or intensity-modulated radiotherapy in patients with esophageal cancers by monitoring the radiation-induced heart damage. Methods Between August 2011 and February 2014, 102 patients with esophageal cancers in our hospital were treated with confomal radiotherapy and conventional radiotherapy, the patients were examined electrocardiogram（ECG）, myocardial enzymes, cardiac troponin I, ultrasonic cardiogram and thorax CT ect before radiation and after radiation and were followed up in three months after radiation. Results The incidence rate of actue radiation-induced heart damage was 79.6%（39 patients） in conventional radiotherapy groups. The incidence rate of actue RIHD was 60.4%（32 patients）. χ^2=3.938, P〈0.05, The difference have statistics significance. Conclusion The patients with esophageal cancers encounted dimensional radiontherapy reduced the damaged of acute heart radiation by limiting reasonably the dose and ranre of radiation.
出处
《中国医药科学》
2015年第2期180-182,共3页
China Medicine And Pharmacy
关键词
食管癌
适形放疗
放射性心脏损伤
Esophagus cancer
Dimensional radiotherapy
Radiation-induced heart damage
