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甲氧氯普胺帽状腱膜下穴位注射预防性治疗月经周期性偏头痛临床观察 被引量:15

Preventive effect on menstrual migraine treated with subgaleal acupoint injection with metoclopramide
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摘要 目的:观察甲氧氯普胺帽状腱膜下穴位注射预防性治疗与口服西药治疗对月经周期性偏头痛的临床疗效差异。方法:将月经期偏头痛患者64例随机分为帽状腱膜下穴位注射组和药物治疗组,每组32例。穴位注射组于月经前10天开始,选取8个头部穴位分2组交替注射,2天注射1次,4次为一疗程,共3个疗程(3个月经周期);药物治疗组口服西比灵(氟桂利嗪)2.5mg,每晚口服1次,疗程为3个月。两组患者均于治疗后3、6个月分别观察镇痛效果、头痛发作频率及时间。结果:治疗后两组患者疼痛视觉模拟评分(VAS评分)均低于治疗前(P<0.01,P<0.05);发作频率及头痛时间均较治疗前降低或减少(均P<0.01);治疗后穴位注射组VAS评分、头痛发作频率及时间较药物治疗组改善显著(均P<0.05)。结论:甲氧氯普胺帽状腱膜下穴位注射预防性治疗月经周期性偏头痛临床效果确切,且优于口服西药西比灵。 Objective To observe the differences in clinical effect on menstrual migraine between subgaleal acu- point injection with metoclopramide and oral administration of medication. Methods Sixty-four patients of men- strual migraine were randomized into a subgaleal acupoint injection group and a medication group, 32 cases in each one. In the subgaleal acupoint injection group, the acupoint injection started 10 days before menstruation. Eight acupoints on the head were selected and injected alternatively in two groups, once every 2 days, 4 treatments made one session and 3 sessions (3 menstrual cycles) were required. In the medication group, flunarizine was applied with oral administration, 2.5 mg each time, once every night. The duration of treatment was 3 months. The anal- gesic effect, frequency and time of pain attack were observed in 3 and 6 months after treatment in the two groups. Results After treatment, VAS scores were lower than those before treatment in the two groups (P〈0.01, P〈 0.05), the attack frequency and pain time were all reduced as compared with those before treatment (all P〈 0.01). After treatment, VAS score, the frequency and time of pain attack in the subgaleal acupoint injection group were improved significantly as compared with the medication group (all P〈0.01). Conclusion The subgaleal acu- point injection with metoclopramide achieves the superior preventive effect in clinical treatment of menstrual mi- graine as compared with flunarizine.
出处 《中国针灸》 CAS CSCD 北大核心 2015年第3期243-246,共4页 Chinese Acupuncture & Moxibustion
关键词 月经周期性偏头痛 穴位注射 甲氧氯普胺 帽状腱膜 氟桂利嗪 menstrual migraine acupoint injection metoclopramide subgalgeal flunarizine
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