摘要
【目的】探讨柴胡疏肝散治疗反流性咽喉疾病的疗效。【方法】将60例反流性咽喉疾病患者随机分为治疗组和对照组各30例。治疗组以柴胡疏肝散为主治疗,对照组以质子泵抑制剂奥美拉唑钠肠溶片治疗,疗程为4周。于治疗前后对2组患者进行反流症状指数量表(reflux symptom index,RSI)及反流体征量表(reflux finding score,RFS)的评分。【结果】(1)治疗后,2组患者的RSI、RFS评分均有一定程度改善,其中RSI评分与治疗前比较差异均有统计学意义(P<0.05)。(2)治疗后,治疗组患者声嘶及咽异物感等症状改善优于对照组,2组治疗前后差值比较,差异有统计学意义(P<0.05)。【结论】柴胡疏肝散对反流性咽喉疾病肝胃不和证患者具有良好的治疗效果,与西药质子泵抑制剂的疗效相当,且在改善症状方面具有一定的优势。
Objective To study the clinical efficacy of Chaihu Shugan Powder for the treatment of patients with laryngopharyngeal reflux disease（ LPRD）. Methods A total of 60 patients confirmed as LPRD were evenly randomized into treatment group and control group. The treatment group was treated with Chaihu Shugan Powder and the control group was treated with proton pump inhibitor Omeprazole Sodium Enteric Tablets. The treatment lasted for 4 weeks. Clinical efficacy of the two groups was evaluated by the changes of reflux symptom index（ RSI） and reflux finding score（ RFS）. Results（ 1） After treatment, RSI and RFS were decreased in both groups, and the differences of RSI were significant as compared with those before treatment（ P〈0.05）.（ 2）After treatment, the relief of hoarseness and foreign body sensation in the throat was superior in the treatment group than that of the control group, the difference before and after treatment was statistically significant in the two groups（ P〈0.05）. Conclusion Both Chaihu Shugan Powder and proton pump inhibitor are effective for the treatment of LPRD with the syndrome of liver-stomach disharmony, and Chaihu Shugan Powder has better effect on relieving symptoms.
出处
《广州中医药大学学报》
CAS
2015年第2期204-207,共4页
Journal of Guangzhou University of Traditional Chinese Medicine
基金
广东省科技厅科技计划项目(编号:2012B031800191)
