摘要
目的比较持续静脉泵入乌拉地尔与持续静脉泵入硝普钠在高血压急症治疗中的临床疗效。方法选择2012年2月~2014年2月我院收治的高血压急症患者88例,随机分为对照组和观察组各44例。对照组给予持续静脉泵入硝普钠治疗,观察组给予持续静脉泵入乌拉地尔治疗。对两组患者治疗后的总有效率,治疗前后收缩压、舒张压、心率的变化及不良反应发生率进行比较。结果 1观察组总有效率（93.2%）明显高于对照组（75.0%,P〈0.05）。2治疗后观察组和对照组收缩压、舒张压及心率均较治疗前显著降低（均P〈0.05）;治疗后观察组在改善心率方面优于对照组（P〈0.05）。3观察组不良反应发生率（9.1%）明显低于对照组（22.6%,P〈0.05）。结论持续静脉泵入乌拉地尔在高血压急症治疗中,可提高临床疗效,改善心率,减少不良反应,值得临床推广应用。
Objective To analyzed the clinical effect of Urapidil through continuous intravenous pump and sodium Nitroprusside through continuous intravenous pump in treatment of hypertensive emergency.Methods 88 patients with hypertensive emergency were randomly divided into control group and observation group.Control group was treated with sodium Nitroprusside through continuous intravenous pump,while observation group was treated with Urapidil through continuous intravenous pump.Total clinical efficacy,changes of systolic blood pressure,diastolic blood pressure and heart rate,and postoperative complications of the patients in two groups were compared.Results Total clinical efficacy of observation group（93.2%）was significantly higher than that of control group（75.0%）（P〈0.05）.Systolic blood pressure and diastolic blood pressure in observation group after treatment were significantly higher than those before treatment（P〈0.05）.Heart rate improvement in observation group after treatment was significantly better than that in control group（P〈0.05）.Postoperative complications of observation group（9.1%）was significantly lower than that of control group（22.6%）（P〈0.05）.Conclusion Urapidil through continuous intravenous pump in the treatment of hypertensive emergency will enhance clinical efficacy,improve heart rate and reduce the incidence of postoperative complications.So it is worth applying in clinic widely.
出处
《西部医学》
2015年第3期356-357,360,共3页
Medical Journal of West China
基金
国家自然科学基金(30971264)
关键词
乌拉地尔
硝普钠
高血压急症
Urapidil
Sodium Nitroprusside
Hypertensive emergency
