摘要
目的探讨鲑鱼降钙素治疗老年糖尿病并发骨质疏松的效果。方法选取70例老年糖尿病并发骨质疏松患者为研究对象,随机分为对照组和观察组,对照组给予碳酸钙D3片治疗,观察组采用碳酸钙D3片联合鲑鱼降钙素治疗,比较两组的疼痛程度、治疗效果及血清BMD、BGP、AKP及PTH含量,记录两组不良反应发生情况。结果观察组治疗后的疼痛程度明显改善,且明显好于对照组(P<0.05);观察组治疗后的BMD、BGP水平高于对照组及治疗前(P<0.05);观察组治疗后的AKP、PTH水平低于对照组及治疗前(P<0.05);观察组总有效率为94.3%,明显高于对照组的77.1%(P<0.05);观察组不良反应发生率明显低于对照组(P<0.05)。结论鲑鱼降钙素治疗老年糖尿病并发骨质疏松的临床效果显著。
Objective To investigate the efficacy of salmon calcitonin in the treatment of senile diabetes complicated with osteoporosis. Methods 70 patients with senile diabetes complicated with osteoporosis were selected as research objects and randomly divided into control group and observation group.Calcium carbonate D3 tablet was used in control group,calcium carbonate D3 tablet combined with salmon calcitonin were applied in observation group.The pain degree,effect and the level of serum BMD,BGP,AKP and PTH in two groups were compared.The adverse reaction in two groups were recorded. Results After treatment,the pain degree of observation group was significantly improved,and significantly better than that of control group（P〈0.05）.After treatment,the level of BMD,BGP in observation group was significantly higher than that in control group and before treatment respectively（P〈0.05）.After treatment,the level of AKP,PTH in observation group was significantly lower than in control group and before treatment respectively（P〈0.05）.Total effective rate of observation group was 94.3%,significantly higher than that of control group（77.1%）（P〈0.05）.The incidence rate of adverse reaction in observation group was significantly lower than that in control group（P〈0.05）. Conclusion The clinical efficacy of salmon calcitonin in the treatment of senile diabetes complicated with osteoporosis is significant.
出处
《中国当代医药》
2015年第6期142-144,共3页
China Modern Medicine
