摘要
目的研究降钙素原（PCT）水平对急性冠脉综合征患者预后的影响,为临床治疗提供依据。方法选取2013年5月至2014年5月该院收治的急性冠脉综合征患者210例,根据PCT水平将患者分为A组（n=121）、B组（n=49）和C组（n=40）,其中A组PCT≤0.05ng/mL,B组0.
Objective To study the influence of procalcitonin（PCT）on the prognosis in the patients with acute coronary syndrome（ACS）to provide the basis for clinic treatment.Methods 210 cases of ACS treated in our hospital from May 2013 to May2014were selected and divided into the group A（n=121）,B（n=49）and C（n=40）according to their PCT levels,the group A：PCT≤0.05ng/mL,the group B：0.05〈PCT〈0.5ng/mL and the group C：PCT≥0.5ng/mL.Then the occurrence rate of the non-ST-elevation myocardial infarction（NSTEMI）or unstable angina（UA）,simple-ST-elevation acute myocardial infarction（STEMI）,cardiogenic shock（CS）complicating STEMI were compared among 3groups.Finally,the correlation between PCT level with the incidence of major adverse cardiac events and the mortality rate was analyzed by using COX regression.Results The occurrence rate of CS in the roup C was significantly higher than that in the group A and B,and the occurrence rate of CS in the group B was significantly higher than that in the group A,the differences were statistical significant（P〈0.05）.The occurrence rate of NSTEMI/UA and STEMI in the group C was significantly lower than that in the group A and B,the difference was also statistical significant（P〈0.05）;the COX regression analysis revealed that the PCT level was positively correlated with the incidence of major adverse cardiac events and the mortality rate（P〈0.05）.Conclusion The PCT level is a high-risk factor of ACS and is closely related with the incidence of major adverse cardiac events and the mortality rate.
出处
《国际检验医学杂志》
CAS
2015年第5期631-632,635,共3页
International Journal of Laboratory Medicine
关键词
降钙素原
急性冠脉综合征
预后
procalcitonin
acute coronary syndrome
prognosis
