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完整肠系膜切除术对结肠癌治疗的临床疗效研究 被引量:5

Study on the clinical effect of the complete mesocolic excision for colon cancer
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摘要 目的研究完整肠系膜切除术对结肠癌治疗的效果,探索结肠癌手术治疗的规范化方法。方法选取2013年1月至2014年6月期间在我院肛肠外科接受CME手术治疗的结肠癌患者40例(CME组),同时取2011年1月至2012年12月期间行传统结肠癌根治术的结肠癌患者40例(对照组),收集其临床资料并进行回顾性分析,比较两组患者术中及术后恢复的相关指标。结果 CME组的术中出血量为128.35±60.05mL,对照组的为159.65±63.28mL,CME组明显少于对照组(P<0.05);CME组的淋巴结清扫数目为32.04±4.65个,对照组为28.74±3.88个,CME组的淋巴结检出数目高于对照组(P<0.05);CME组的腹腔引流液为196.37±18.95mL,而对照组为162.18±16.72mL,CME组的腹腔引流液明显多对照组(P<0.05);但两组患者在手术时间、排气排粪时间、进食时间、术后拔除引流管时间、住院时间、下地活动时间方面无明显差异(P>0.05);CME组的术后并发症发生率为12.50%,而对照组为17.50%,两组间无统计学差异(P>0.05)。结论完整肠系膜切除术治疗结肠癌比传统结肠癌根治术有明显的优势,且不会增加术后并发症的发生,可用于结肠癌的治疗。 Objective To study the curative effect of the complete mesocolic excision(CME)for colon cancer,and to explore the standardized surgical methods of the colon cancer.Methods Forty patients with colon cancer for CME surgical treatment in our hospital department of anorectal section from January 2013 to June 2014 were selected,and 40 patients with colon cancer underwent the conventional radical resection of colon cancer in January 2011 to December 2012 were analyzed,retrospectively.The postoperative recovery related indicators,the preoperative and postoperative relevant parameters were observed in the two groups.Results The amount of bleeding in the CME group was 128.35±60.05 ml,and it was 159.65±63.28 ml in the control group.The volume of bleeding in the CME group was significantly less than the control group(P〈0.05).In the CME group,the number of examined lymph nodes were 32.04±4.65,however,there were only 28.74±3.88 in the control group,which were lower than the CME group(P〈0.05).The peritoneal drainage fluid in CME group was 196.37±18.95 ml,while the control group was162.18±16.72 ml,and the peritoneal fluid in CME group was significantly more than the control group(P0.05).But the operative time,evacuation time,defecation time,eating time,postoperative extubation time,hospitalization time and ambulation time of patients in both groups had no significant difference(P〉0.05).The incidence of the postoperative complications was 12.50% in the CME group,and17.50%in the control group,and there were no significant difference between the two groups(P〉0.05).Conclusion The CME has obvious advantages in the treatment of colon cancer compared with the traditional radical resection,meanwhile it does not increase the incidence of postoperative complications,so it can be used for the treatment of colon cancer.
出处 《结直肠肛门外科》 2014年第5期328-331,共4页 Journal of Colorectal & Anal Surgery
关键词 完整肠系膜切除术 结肠癌 治疗效果 并发症 Complete mesocolic excision Colon cancer Therapeutic effect Complication
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