摘要
目的:观察伤科止痛膏外敷对四肢闭合性骨折围手术期疼痛、肿胀和血液流变学的影响。方法:将50例四肢闭合性骨折患者随机平均分为治疗组和对照组。治疗组25例予以外敷伤科止痛膏,对照组25例予以外敷体积分数75%医用酒精,观察两组患者皮肤皱褶出现时间、肿胀程度、疼痛情况、血液流变学等指标以及不良反应。结果:1首次出现皮肤皱褶时间:治疗组为(4.34±0.77)d,对照组为(5.42±1.15)d,两组比较,差异有统计学意义(P<0.01)。2肿胀程度:治疗组治疗后的24 h、48 h、72 h,改善肿胀程度方面明显优于对照组(P<0.01)。3疼痛评分:治疗后两组第1天、第2天、第3天评分比较,治疗组均优于对照组(P<0.01)。4血液流变学指标:治疗后,治疗组血浆黏度、全血高切黏度、全血中切黏度、全血低切黏度均显著低于对照组(P<0.01)。5不良反应:两组均未发生明显不良反应。结论:伤科止痛膏在改善骨折围手术期肿胀、疼痛等方面疗效确切,对骨折早期血液流变学的改善作用显著。
Objective： Observe the effect of Shangke Zhitong ointment on peroperative period sore pain and haemorheology of closed fractures. Methods： 50 cases with closed fracture were randomly divided into treatment group and control group equally. The treatment group was treated with external Shangke Zhitong ointment and control group was treated with topical 75% of medical alcohol. Observe the appearance of skin fold,swelling degree,pain,blood rheology indexes and adverse reaction of two groups. Results： The appearance time of skin fold was（ 4. 34 ± 0. 77） d in treatment group and（ 5. 42 ± 1. 15） d in control group. Compared of the two groups,the difference was statistically significant（ P〈0. 01）. The swelling degree improvement of treatment group was better than that of control group after treatment of 24 h,48 h,72 h（ P〈0. 01）. Compared the pain score of two groups after treatment day 1,day 2,day 3,treatment group was better than control group（ P〈0. 01）. The blood plasma viscosity,whole blood high shear viscosity,whole blood viscosity and whole blood low shear viscosity of treatment group were significantly lower than that of control group（ P〈0. 01）. Two groups had no obvious adverse reaction. Conclusion： Shangke Zhitong ointment in improving the fracture during swelling,pain during the operation has indeed curative effect and significant improvement of blood rheology of the early fracture.
出处
《中医学报》
CAS
2015年第3期360-362,共3页
Acta Chinese Medicine
