摘要
目的探讨地佐辛超前镇痛用于下肢全麻手术的临床研究。方法选择2013年5月至2014年5月在沧州中西医结合医院行下肢全麻手术的78例患者作为研究对象,将其随机分为观察组40例、对照组38例,2组患者均采取全麻手术,观察组同时给予地佐辛超前镇痛,比较2组患者术后疼痛情况、镇痛情况以及不良反应发生情况。结果术后4h,2组患者VAS评分差异无统计学意义(P>0.05),而术后6h、术后12h以及术后24h,观察组患者VAS评分均明显低于对照组,差异有统计学意义(P<0.05);术后4h、术后24h,2组患者术后镇静评分差异无统计学意义(P>0.05),术后8h、术后12h,观察组镇静评分明显低于对照组,差异具有统计学意义(P<0.05);观察组发生不良反应患者10例(25.00%),对照组发生不良反应患者18例(47.37%),2组比较,差异有统计学意义(P<0.05)。结论在下肢全麻手术患者中运用地佐辛超前镇痛,有利于减轻患者术后疼痛、改善患者术后镇静情况以及降低手术不良反应发生率,值得临床推广运用。
Objective To investigate the clinical research of general anesthesia for lower limb operation dezocine preemptive analgesia. Methods 78 cases of lower limb surgery under general anesthesia patients were selected from May, 2013 to May, 2014 in our hospital as the research object, the patients were randomly divided into observation group（40 cases） and control group（38 cases）, two group patients were all taken surgery under general anesthesia, the patients of the observation group meanwhile given dezocine preemptive analgesia. The occurrence of pain, analgesia and the adverse reaction of patients after operation were compared between the two groups. Results The postoperative 4h, VAS in the two groups were not statistically different（P〉0.05）, and after operation for 6h, postoperative 12h and after operation for 24h, patients in group VAS score were significantly lower than that of the control group, with significant difference（P〈0.05）, after operation for 4h, 24h, two groups of patients sedation score was not significant difference（P〈0.05）, after operation for 8h, postoperative 12h, sedation score of observation group was significantly lower than that of the control group, with statistically significant difference（P〈0.05）, 10 cases of patients in the observation group occurred adverse reactions（25%）, 18 patients in the control group occurred adverse reactions（47.37%）, compared with two groups, there was statistically differences（P〈0.05）. Conclusion Applying dezocine preemptive analgesia in patients with lower extremity anesthesia before the operation are beneficial to the patients to improve pain, relieve patients postoperative sedation and reduce the incidence of adverse reaction operation, which is worthy of clinical application.
出处
《医学研究与教育》
CAS
2015年第1期44-47,共4页
Medical Research and Education
基金
沧州市科学技术研究与发展计划项目(131302212)
关键词
地佐辛
超前镇痛
下肢手术
dezocine
preemptive analgesia
lower extremity operation
