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2型糖尿病中医证型流行病学调查及其中医病因病机初探 被引量:118

Initial exploration on traditional Chinese medicine syndrome type epidemiological investigation and etiology and pathogenesis of type 2 diabetes mellitus
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摘要 目的:依据流行病问卷发现2型糖尿病常见证型及各型所占比例,探讨各证型与客观指标的关系。方法:流行病问卷调查2型糖尿病患者428例,对428例2型糖尿病患者中医辨证,归属于6个中医证型,观察记录中医证候、身体质量指数(BMI)、肝功能、血脂、血糖等相关指标。结果:428例患者中气阴两虚型最多(264例,占61.7%)。各中医证型的发病的年龄层多有不同,早期多为肺热津伤型,中晚期多为阴阳两虚及气阴两虚兼瘀证;糖尿病病程比较,阴阳两虚型病程最长;指标比较空腹血糖(FBG)和餐后血糖水平在阴虚火旺型最高;阴虚火旺型糖化血红蛋白(Hb A1c)水平最高;糖尿病足、糖尿病周围神经病变(DPN)发生率较高,多个证型均有发生。结论:不同中医证型发病期有显著差异性,气阴两虚为常见证型,同时2型糖尿病与BMI、血脂肝功能指数具有一定相关性,且中晚期糖尿病多具有并发症产生。 Objective: To find out the common syndrome types and the proportion of each syndrome types of type 2 diabetes mellitus and investigate the relationship between each syndrome type and objective indicators. Methods: Four hundred twenty-eight patients with type 2 diabetes mellitus were surveyed with epidemiological questionnaire. Four hundred twenty-eight patients with type 2 diabetes mellitus could be concluded in 6 syndrome types according to and syndrome differentiation, and the syndromes, BMI, liver function, blood fat, blood glucose and so on were all observed and recorded. Results: The most common syndrome of 428 patients with type 2 diabetes mellitus was syndrome of deficiency of both qi and yin (246 cases, 61.7%). Each type of onset of TCM there were many different ages, mostly hyperactivity jin injury early, medium and late, mostly yin and yang yin deficiency Syndrome and silt; duration of diabetes compared with the longest duration of yin and yang type; index compares fasting blood glucose (FBG) and postprandial glucose levels highest in wang; wang glycated hemoglobin (HbAlc) the highest level; diabetic foot, diabetic peripheral neuropathy (DPN) higher incidence of multiple syndromes have occurred. Conclusion: There is significant difference in the period of disease among different syndrome types, and syndrome of deficiency of both qi and yin is the most common syndrome. There is a certain correlation among type 2 diabetes mellitus, BMI, blood fat and liver function, and complications often occur in middle-late stage of diabetes.
出处 《中华中医药杂志》 CAS CSCD 北大核心 2015年第3期732-735,共4页 China Journal of Traditional Chinese Medicine and Pharmacy
关键词 2型糖尿病 中医证型 舌苔 脉象 慢性并发症 Type 2 diabetes mellitus Chinese medical syndrome pattern Tongue fur Pulse Chronic complications
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