期刊文献+

高血压患者心血管内分泌激素和胰岛素的抵抗作用分析 被引量:3

下载PDF
导出
摘要 目的:分析高血压患者的心血管内分泌激素和胰岛素的抵抗作用。方法:选择41例高血压患者作为实验组,41例无高血压病情的健康体检者作为对照组。经过6周的临床实验,对两组实验对象在相同条件下的t-PA、ANP、PAI活性、IS、ET等水平指标进行检测分析。结果:在PAI、ET、ANP各项测定的数据指标上实验组明显高于对照组,t-PA与IS的数据指标明显低于对照组,两组差异比较有统计学意义(P<0.05)。结论:高血压疾病的发生与心血管内分泌激素和胰岛素的抵抗作用有密切关系。
作者 李丽萍
出处 《医学理论与实践》 2015年第4期466-467,共2页 The Journal of Medical Theory and Practice
  • 相关文献

参考文献6

二级参考文献134

  • 1杨,施仲伟.糖尿病或糖耐量异常高血压患者左室收缩功能[J].高血压杂志,2006,14(7):535-538. 被引量:3
  • 2[1]Reaven G M. Role of insulin resistance in human disease (syndrome X):An expanded definition.Annu Rev Med,1993,44(2):121-125.
  • 3[2]Giles T D.Antihypertensive therapy and cardiovascular rike,are all antihypertensives equal? Hypertension,1992,19(S 1):Ⅰ 124-126.
  • 4[3]Defronzo R A.Insulin resistance,hyperinsulinemia,and coronary artery disease:A complex metabolic web.J Cardiovase Pharmacol,1992,20(S 11):S 1-3.
  • 5[4]Laakso M.How good a marker is insulin level for insulin resistance?Am J Epidemiol,1993,137(9):959-961.
  • 6[1]Gordero A,Laclausta M,Leon M,et al.Prehypertension is associated with insulin resistance state and not with an initial renal function impairment[J].Am J Hypertension,2006,19:186-196.
  • 7[2]Chen YE,Fu M,Zhang J,et al.Peroxisome proliferator activated receptors and the cardiovascular system[J].Vitamin& Hormones,2003,66:157-188.
  • 8[3]Elchebly M,Payette P,Michaliszyn E,et al.Increased insulin sensitivity and obesity resistance in mice lacking the protein tyrosine phosphatase-1B gene[J].Science,1999,283:1544-1548.
  • 9[4]Gum RJ,Gaede LL,Koterski SL,et al.Reduction of protein tyrosine phosphatase 1B increases insulin-dependent signaling in ob/ob mice[J].Diabetes,2003,52:21-28.
  • 10[5]Palmer ND,Bento JL,Mychaleckyj JC,et al.Association of protein tyrosine phosphatase 1B gene polymorphisms with measures of glucose homeostasis in Hispanic Americans:the insulin resistance atherosclerosis study (IRAS) family study[J].Diabe tes,2004,53:3013-3019.

共引文献15

同被引文献25

引证文献3

二级引证文献20

相关作者

内容加载中请稍等...

相关机构

内容加载中请稍等...

相关主题

内容加载中请稍等...

浏览历史

内容加载中请稍等...
;
使用帮助 返回顶部